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Cytomegalovirus
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Microbiology

Virology

Introduction to viruses
Viral structure and functions
DNA viruses
Varicella zoster virus
Cytomegalovirus
Epstein-Barr virus (Infectious mononucleosis)
Human herpesvirus 8 (Kaposi sarcoma)
Herpes simplex virus
Human herpesvirus 6 (Roseola)
Adenovirus
Parvovirus B19
Hepatitis B and Hepatitis D virus
Human papillomavirus
Poxvirus (Smallpox and Molluscum contagiosum)
BK virus (Hemorrhagic cystitis)
JC virus (Progressive multifocal leukoencephalopathy)
RNA viruses
Poliovirus
Coxsackievirus
Rhinovirus
Hepatitis A and Hepatitis E virus
Hepatitis B and Hepatitis D virus
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Mumps virus
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Human parainfluenza viruses
Dengue virus
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Coronaviruses
HIV (AIDS)
Human T-lymphotropic virus
Ebola virus
Rabies virus
Rubella virus
Eastern and Western equine encephalitis virus
Lymphocytic choriomeningitis virus
Hantavirus
Prions and virioids
Prions (Spongiform encephalopathy)

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Cytomegalovirus

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High Yield Notes
10 pages
Flashcards

Cytomegalovirus

25 flashcards
Questions

USMLE® Step 1 style questions USMLE

2 questions
Preview

A 17-year-old girl presents for evaluation of sore throat and fatigue. The patient's symptoms have been ongoing for the past week. According to the patient, “I think I picked up a bug from my partner, he had a similar illness about three-weeks ago.” The patient is otherwise healthy and does not take any medications. Temperature is 38.2°C (100.8°F), pulse is 80/min, respirations are 14/min, and blood pressure is 125/71 mmHg. Physical examination demonstrates posterior auricular and posterior cervical lymphadenopathy, as well as bilateral tonsillar swelling. A heterophile antibody screen is negative. Which of the following is the most likely pathogen responsible for this patient’s symptoms?

External References
Summary

Cytomegalovirus (CMV), also known as human herpes 5, is a double-stranded DNA virus. It is usually asymptomatic in immunocompetent individuals, but can present with severe diseases in immunocompromised individuals such as those with HIV/AIDS. It can cause retinitis, esophagitis, and retinitis pneumonia. On microscopic examination, infected cells can present with characteristic "owl eye" inclusion bodies. CMV is spread through body fluids such as saliva, urine, and sexual contact but can also be spread via transplanted organs.