Summary of Cytomegalovirus
The cytomegalovirus, also known as human herpesvirus 5, is an enveloped, double stranded, linear DNA virus that causes infectious mononucleosis with a negative Monospot test. It characteristically causes esophagitis, retinitis, and atypical pneumonia in immunocompromised patients, with "owl eye" inclusion bodies in infected cells. It can also lie latent in mononuclear cells, and become reactivated in times of immunosuppression or severe systemic disease. It is spread through saliva, urine, sexual contact, or transplanted organs. Treatment is with ganciclovir, or with foscarnet/cidofovir if ganciclovir resistance.
High Yield Notes
10 pages


25 flashcards

are the antiviral drugs used to treat cytomegalovirus retinitis in patients with AIDS.


USMLE® Step 1 style questions USMLE

7 questions

USMLE® Step 2 style questions USMLE

6 questions

A 52-year-old man comes to the ophthalmology clinic because of black spots in his vision for 2 weeks. He states that the spots are not there all the time, but are very annoying. The spots always go away if he closes his right eye. Medical history includes renal transplant for which he takes tacrolimus, mycophenolate, and prednisolone. Examination shows visual acuity in the right eye is 20/100 and the left eye is 20/20. Fundus examination is pictured. Which of the following is the most likely causative agent?

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