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Degenerative disc disease

Summary of Degenerative disc disease
Degenerative disc disease is a pathologic process of degeneration of the intervertebral discs. Disc degeneration is a disease of aging, and though for most people is not a problem, in certain individuals a degenerated disc can cause severe chronic pain if left untreated. The typical radiographic findings are disc space narrowing, vacuum disc, end plate sclerosis, and osteophyte formation.  

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Pathology

Musculoskeletal system

Pediatric musculoskeletal conditions
Musculoskeletal injuries and trauma
Bone disorders
Joint disorders
Muscular disorders
Neuromuscular junction disorders
Other autoimmune disorders
Musculoskeletal system pathology review

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Degenerative disc disease

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High Yield Notes
15 pages
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Degenerative disc disease

8 flashcards
Questions

USMLE® Step 1 style questions USMLE

1 questions

USMLE® Step 2 style questions USMLE

1 questions
Preview

A 67-year-old man comes to the clinic because of low back and buttocks pain for 3 weeks. He has no history of trauma, lower limb weakness, stool, or urine incontinence. He is a retired construction worker. He has type II diabetes and receives metformin twice per day. Physical examination shows lower back tenderness, decreased sensation in the foot bilaterally, mild weakness of the pedal pulse bilaterally, and normal muscle tone. Straight leg test is negative. Lower back X-ray shows no abnormalities. Lower back MRI shows decreased signal intensity of lumbar inter-vertebral discs on T1-weighted images. Which of the following is the most likely cause of the patient's symptoms?