Endometrial cancer
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Endometrial cancer
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Diabetes mellitus p. 352-360
endometrial cancer risk p. 665
Endometrial cancer
Lynch syndrome and p. 397
tamoxifen and p. 450
tumor suppressor genes and p. 222
Estrogen p. 654, 680
endometrial carcinoma p. 665
Hypertension p. 306
endometrial cancer p. 665
Lynch syndrome p. 397
endometrial cancer p. 665
Obesity
endometrial cancer p. 665
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Endometrial carcinoma, or endometrial cancer, is when malignant or cancer cells arise in the glands of the endometrium, the lining of the uterus.
The uterus is a hollow organ that sits behind the urinary bladder and in front of the rectum.
The top of the uterus above the openings of the fallopian tubes is called the fundus, and the region below the openings is called the uterine body.
The uterus tapers down into the uterine isthmus and finally the cervix, which protrudes into the vagina.
Zooming into the cervix, there are two openings, a superior opening up top, and an inferior opening down below, both of which have mucus plugs to keep the uterus closed off except during menstruation and right before ovulation.
The uterus is anchored to the sacrum by utero-sacral ligaments, to the anterior body wall by round ligaments, and it’s supported laterally by cardinal ligaments as well as the mesometrium, which is part of the broad ligament.
Sources
- "Robbins Basic Pathology" Elsevier (2017)
- "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
- "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
- "CURRENT Medical Diagnosis and Treatment 2020" McGraw Hill Professional (2019)
- "Adjuvant radiotherapy for stage I endometrial cancer" Cochrane Database of Systematic Reviews (2012)
- "Endometrial cancer" BMJ (2011)
- "Developmental Biology of Uterine Glands1" Biology of Reproduction (2001)
- "Diagnosis and Management of Endometrial Cancer" American family physician (2016)
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