USMLE® Step 1 style questions USMLE
A 50-year-old woman comes to her primary care provider for progressive dysphagia and loss of 15 pounds over the past three months. Over the past three months, she has been finding it increasingly difficult to swallow solid foods and she is now complaining of difficulty swallowing fluids. She has a medical history of obesity, gastroesophageal reflux disease (GERD), and metaplasia of the lower esophagus involving replacement of stratified squamous epithelium with columnar epithelium and goblet cells. Which of the following is the most likely diagnosis?