Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review

863views

00:00 / 00:00

Videos

Notes

Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review

Subspeciality surgery

Cardiothoracic surgery

Coronary artery disease: Clinical (To be retired)

Valvular heart disease: Clinical (To be retired)

Pericardial disease: Clinical (To be retired)

Aortic aneurysms and dissections: Clinical (To be retired)

Chest trauma: Clinical (To be retired)

Pleural effusion: Clinical (To be retired)

Pneumothorax: Clinical (To be retired)

Lung cancer: Clinical (To be retired)

Anatomy clinical correlates: Thoracic wall

Anatomy clinical correlates: Heart

Anatomy clinical correlates: Pleura and lungs

Anatomy clinical correlates: Mediastinum

Adrenergic antagonists: Beta blockers

ACE inhibitors, ARBs and direct renin inhibitors

cGMP mediated smooth muscle vasodilators

Lipid-lowering medications: Statins

Lipid-lowering medications: Fibrates

Miscellaneous lipid-lowering medications

Antiplatelet medications

Plastic surgery

Benign hyperpigmented skin lesions: Clinical (To be retired)

Skin cancer: Clinical (To be retired)

Blistering skin disorders: Clinical (To be retired)

Bites and stings: Clinical (To be retired)

Burns: Clinical (To be retired)

ENT (Otolaryngology)

Anatomy clinical correlates: Olfactory (CN I) and optic (CN II) nerves

Anatomy clinical correlates: Trigeminal nerve (CN V)

Anatomy clinical correlates: Facial (CN VII) and vestibulocochlear (CN VIII) nerves

Anatomy clinical correlates: Glossopharyngeal (CN IX), vagus (X), spinal accessory (CN XI) and hypoglossal (CN XII) nerves

Anatomy clinical correlates: Skull, face and scalp

Anatomy clinical correlates: Ear

Anatomy clinical correlates: Temporal regions, oral cavity and nose

Anatomy clinical correlates: Bones, fascia and muscles of the neck

Anatomy clinical correlates: Vessels, nerves and lymphatics of the neck

Anatomy clinical correlates: Viscera of the neck

Antihistamines for allergies

Neurosurgery

Stroke: Clinical (To be retired)

Seizures: Clinical (To be retired)

Headaches: Clinical (To be retired)

Traumatic brain injury: Clinical (To be retired)

Neck trauma: Clinical (To be retired)

Brain tumors: Clinical (To be retired)

Lower back pain: Clinical (To be retired)

Anatomy clinical correlates: Olfactory (CN I) and optic (CN II) nerves

Anatomy clinical correlates: Oculomotor (CN III), trochlear (CN IV) and abducens (CN VI) nerves

Anatomy clinical correlates: Trigeminal nerve (CN V)

Anatomy clinical correlates: Facial (CN VII) and vestibulocochlear (CN VIII) nerves

Anatomy clinical correlates: Glossopharyngeal (CN IX), vagus (X), spinal accessory (CN XI) and hypoglossal (CN XII) nerves

Anatomy clinical correlates: Vertebral canal

Anatomy clinical correlates: Spinal cord pathways

Anatomy clinical correlates: Cerebral hemispheres

Anatomy clinical correlates: Anterior blood supply to the brain

Anatomy clinical correlates: Cerebellum and brainstem

Anatomy clinical correlates: Posterior blood supply to the brain

Anticonvulsants and anxiolytics: Barbiturates

Anticonvulsants and anxiolytics: Benzodiazepines

Nonbenzodiazepine anticonvulsants

Migraine medications

Osmotic diuretics

Antiplatelet medications

Thrombolytics

Ophthalmology

Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review

Eye conditions: Retinal disorders: Pathology review

Eye conditions: Inflammation, infections and trauma: Pathology review

Anatomy clinical correlates: Olfactory (CN I) and optic (CN II) nerves

Anatomy clinical correlates: Oculomotor (CN III), trochlear (CN IV) and abducens (CN VI) nerves

Anatomy clinical correlates: Eye

Orthopedic surgery

Joint pain: Clinical (To be retired)

Lower back pain: Clinical (To be retired)

Anatomy clinical correlates: Clavicle and shoulder

Anatomy clinical correlates: Axilla

Anatomy clinical correlates: Arm, elbow and forearm

Anatomy clinical correlates: Wrist and hand

Anatomy clinical correlates: Median, ulnar and radial nerves

Anatomy clinical correlates: Bones, joints and muscles of the back

Anatomy clinical correlates: Hip, gluteal region and thigh

Anatomy clinical correlates: Knee

Anatomy clinical correlates: Leg and ankle

Anatomy clinical correlates: Foot

Trauma surgery

Traumatic brain injury: Clinical (To be retired)

Neck trauma: Clinical (To be retired)

Chest trauma: Clinical (To be retired)

Abdominal trauma: Clinical (To be retired)

Urology

Penile conditions: Pathology review

Prostate disorders and cancer: Pathology review

Testicular tumors: Pathology review

Kidney stones: Clinical (To be retired)

Renal cysts and cancer: Clinical (To be retired)

Urinary incontinence: Pathology review

Testicular and scrotal conditions: Pathology review

Anatomy clinical correlates: Male pelvis and perineum

Anatomy clinical correlates: Female pelvis and perineum

Anatomy clinical correlates: Other abdominal organs

Anatomy clinical correlates: Inguinal region

Androgens and antiandrogens

PDE5 inhibitors

Adrenergic antagonists: Alpha blockers

Vascular surgery

Peripheral vascular disease: Clinical (To be retired)

Leg ulcers: Clinical (To be retired)

Aortic aneurysms and dissections: Clinical (To be retired)

Anatomy clinical correlates: Anterior and posterior abdominal wall

Adrenergic antagonists: Beta blockers

Lipid-lowering medications: Statins

Lipid-lowering medications: Fibrates

Miscellaneous lipid-lowering medications

Antiplatelet medications

Thrombolytics

Assessments

Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review

USMLE® Step 1 questions

0 / 7 complete

Questions

USMLE® Step 1 style questions USMLE

of complete

A 56-year-old man presents to the emergency department with severe left eye pain that started while he was at work. The patient is a radiologist and spends most of the day in a dark room reading films. Past medical history is noncontributory, and he does not take any medications. Physical examination of the left eye is shown below. Intraocular pressure is 39 mmHg in the left eye and 18 mmHg in the right eye. Which of the following pharmacologic agents is contraindicated in the treatment of this patient’s condition?

Image reproduced from Wikimedia Commons

Transcript

Contributors

Antonia Syrnioti, MD

Antonella Melani, MD

Sam Gillespie, BSc

Tina Collins

Talia Ingram, MSMI, CMI

At the ophthalmology clinic, 61-year-old Pedro presents with vision impairment that has been progressive over the past couple of years. He denies experiencing any pain. His past medical history is significant for type 2 diabetes mellitus. Physical examination shows bilateral clouding of the lens.

Next to him, 68-year-old Eileen comes in. She complains that, about an hour ago she started experiencing excruciating pain in her right eye, accompanied by blurry vision and seeing halos around bright lights. Eileen also tells you that she has since vomited twice. On clinical examination, her right eye is red, with a dilated pupil that fails to react to light. Her left eye appears unremarkable.

Based on the initial presentation, both Pedro and Eileen have some form of eye condition. But first, a bit of physiology. If we take a closer look at a cross-section of an eye, we can see that it’s split into three different chambers: anterior, posterior, and vitreous. The anterior chamber includes the area from the cornea to the iris. The posterior chamber is a really narrow space between the iris and the lens. Finally, the much larger vitreous chamber includes the space between the lens and the back of the eye.

Now, both the anterior and posterior chambers are located in the anterior segment of the eye, while the vitreous chamber is part of the posterior segment of the eye. Both chambers in the anterior segment, that is, the anterior and posterior chambers, are filled with a clear watery fluid called aqueous humor, while the vitreous chamber is filled with a clear but thicker fluid called the vitreous humor.

Okay, let’s start with what’s probably the most common group of eye conditions, so refractive errors. Normally, when the eye is in a relaxed state, the refractive power of the cornea and lens help focus light onto the retina. The retina is like a movie screen and the distance from the projector is the axial length of the eye. If it’s too close or too far from the projector, the image will end up looking blurry or out of focus. When the lens and cornea can focus light perfectly on the retina, it’s called emmetropia.

Sources

  1. "Robbins Basic Pathology" Elsevier (2017)
  2. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  3. "Epidemiology of myopia" Eye (2014)
  4. "Primary Care Optometry" Elsevier Health Sciences (2007)
  5. "Age-related cataract" The Lancet (2005)
  6. "Epidemiology of cataract in childhood: A global perspective" Journal of Cataract and Refractive Surgery (1997)
  7. "Glaucoma: the retina and beyond" Acta Neuropathologica (2016)
  8. "Glaucoma" Primary Care: Clinics in Office Practice (2015)
  9. "Color Atlas and Synopsis of Clinical Ophthalmology -- Wills Eye Institute -- Glaucoma" Lippincott Williams & Wilkins (2012)
Elsevier

Copyright © 2023 Elsevier, except certain content provided by third parties

Cookies are used by this site.

USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.

RELX