Fetal hydantoin syndrome

Summary of Fetal hydantoin syndrome

Fetal hydantoin syndrome, also called fetal dilantin syndrome is a group of defects caused to the developing fetus by exposure to the teratogenic effects of phenytoin or carbamazepine. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy.

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Fetal hydantoin syndrome

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Fetal hydantoin syndrome

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USMLE® Step 1 style questions USMLE

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USMLE® Step 2 style questions USMLE

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Preview

A 2-week-old newborn is brought into the pediatrician's office for his first well-child visit. During the appointment, the mother is concerned that he is quite small, even for a baby, and that his head seems especially small. On physical examination the newborn is found to be below the 5^th percentile for both length and head circumference. The pediatrician asks the mother if she drank during pregnancy which she denies. She then reveals that she has epilepsy and was taking her medication at regular dose throughout the pregnancy. Based on the newborn's presentation, which of the following drugs is most likely to cause his condition?

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