Free water clearance
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Free water clearance
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Alpha 1-antitrypsin deficiency
Anatomy clinical correlates: Pleura and lungs
Gas exchange in the lungs, blood and tissues
Abdominal pain: Clinical
Kidney stones: Clinical
Renal system anatomy and physiology
Hydration
Body fluid compartments
Movement of water between body compartments
Renal clearance
Glomerular filtration
TF/Px ratio and TF/Pinulin
Measuring renal plasma flow and renal blood flow
Regulation of renal blood flow
Tubular reabsorption and secretion
Tubular secretion of PAH
Tubular reabsorption of glucose
Urea recycling
Tubular reabsorption and secretion of weak acids and bases
Proximal convoluted tubule
Loop of Henle
Distal convoluted tubule
Renin-angiotensin-aldosterone system
Sodium homeostasis
Potassium homeostasis
Phosphate, calcium and magnesium homeostasis
Osmoregulation
Antidiuretic hormone
Kidney countercurrent multiplication
Free water clearance
Vitamin D
Erythropoietin
Physiologic pH and buffers
Buffering and Henderson-Hasselbalch equation
The role of the kidney in acid-base balance
Acid-base map and compensatory mechanisms
Respiratory acidosis
Metabolic acidosis
Plasma anion gap
Respiratory alkalosis
Metabolic alkalosis
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Free water clearance
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Summary
Free water is distilled water that is free of any solutes. Free water clearance (CH2O) refers to the amount of free water that the kidneys excreted out of the blood plasma per day. Free water is normally filtered at the level of the thick ascending limb and the early distal tubule of a nephron. Measuring free water clearance is one method for assessing the kidney's function.
Sources
- "Medical Physiology" Elsevier (2016)
- "Physiology" Elsevier (2017)
- "Human Anatomy & Physiology" Pearson (2018)
- "Principles of Anatomy and Physiology" Wiley (2014)
- "The development of the clearance concept" J Nephrol (2004)
- "The current place of urea kinetic modelling with respect to different dialysis modalities" Nephrology Dialysis Transplantation (1998)