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Laboratory Value | Result |
Hematologic | |
Leukocyte count | 6,500/mm3 |
Platelet count | 250,000/mm3 |
Hemoglobin | 9.6 g/dL |
Mean corpuscular volume (MCV) | 84 fL |
Mean corpuscular hemoglobin concentration (MCHC) | 42 g/dL (normal 32-36 g/dL) |
Red cell distribution width (RDW) | 15% |
Reticulocyte count | 9.1% |
2024
2023
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2021
hereditary spherocytosis p. 415
hereditary spherocytosis p. 415
in anemia taxonomy p. 423
spherocytes in p. 420
hereditary spherocytosis p. 415
hereditary spherocytosis p. 415
Hereditary spherocytosis (HS) is an autosomal dominant genetic disorder in which red blood cells are sphere-shaped instead of having the normal biconcave shape. These abnormal red blood cells break down prematurely, which can lead to anemia. Also, because of their abnormal shape, red blood cells in spherocytosis don't move through small blood cells efficiently as normal ones do, which can affect tissue oxygenation. People with hereditary spherocytosis can present with jaundice, splenomegaly, and features of anemia like pallor and fatigue.
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