USMLE® Step 1 style questions USMLE
A 22-year-old woman comes to her physician due to weight loss and fatigue for two months. The patient reports night sweats and high fevers, stating that she has been “soaking the bed sheets through” at night. The patient has no significant past medical history. Vital signs are within normal limits. Physical examination reveals nontender cervical and axillary lymphadenopathy. Which of the following clinical features favors a diagnosis of Hodgkin lymphoma over non-Hodgkin lymphoma?