00:00 / 00:00
0 / 5 complete
Hyperkalemia is often asymptomatic, but it can cause symptoms like palpitations, paresthesias, and muscle weakness.
Ultimately if hyperkalemia is severe enough, it can lead to a flaccid paralysis that starts in the lower extremities and ascends upward.
Whenever potassium levels are above 5 mEq/L, the first to do is an EKG.
If the EKG is normal and the individual doesn’t have symptoms of hyperkalemia, and if there’s no apparent cause of hyperkalemia, then it may be due to pseudohyperkalemia. This happens when potassium moves out of the cells during or after a blood draw.
For example, potassium gets released from muscle cells during muscle contraction, so if a person repeatedly clenches their fist during the blood draw, then potassium levels can rise - in fact, they can go up by up to 2 mEq/L in that forearm!
Also during blood drawing, some of the red cells can be harmed and release potassium.
Pseudohyperkalemia can also happen when there’s thrombocytosis or leukocytosis.
For example in chronic lymphocytic leukemia, the lymphocytes are frail, so they break easily and release potassium. The key is to simply repeat the serum potassium level and to obtain a CBC.
If pseudohyperkalemia is ruled out, then there’s a true hyperkalemia.
There may be EKG changes, but they don’t always correlate with the severity and progression of hyperkalemia.
Copyright © 2023 Elsevier, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
Cookies are used by this site.
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.