Hyperlipidemia

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Hyperlipidemia

Biochemistry

Biochemistry and metabolism

Glycolysis

Citric acid cycle

Electron transport chain and oxidative phosphorylation

Gluconeogenesis

Glycogen metabolism

Pentose phosphate pathway

Physiological changes during exercise

Amino acid metabolism

Nitrogen and urea cycle

Fatty acid synthesis

Fatty acid oxidation

Ketone body metabolism

Cholesterol metabolism

Metabolic disorders

Essential fructosuria

Hereditary fructose intolerance

Galactosemia

Pyruvate dehydrogenase deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency

Lactose intolerance

Glycogen storage disease type I

Glycogen storage disease type II (NORD)

Glycogen storage disease type III

Glycogen storage disease type IV

Glycogen storage disease type V

Leukodystrophy

Metachromatic leukodystrophy (NORD)

Krabbe disease

Gaucher disease (NORD)

Niemann-Pick disease types A and B (NORD)

Niemann-Pick disease type C

Fabry disease (NORD)

Tay-Sachs disease (NORD)

Mucopolysaccharide storage disease type 1 (Hurler syndrome) (NORD)

Mucopolysaccharide storage disease type 2 (Hunter syndrome) (NORD)

Cystinosis

Hartnup disease

Alkaptonuria

Ornithine transcarbamylase deficiency

Phenylketonuria (NORD)

Cystinuria (NORD)

Homocystinuria

Maple syrup urine disease

Abetalipoproteinemia

Familial hypercholesterolemia

Hypertriglyceridemia

Hyperlipidemia

Disorders of carbohydrate metabolism: Pathology review

Disorders of fatty acid metabolism: Pathology review

Dyslipidemias: Pathology review

Glycogen storage disorders: Pathology review

Lysosomal storage disorders: Pathology review

Disorders of amino acid metabolism: Pathology review

Assessments

Hyperlipidemia

Flashcards

0 / 20 complete

USMLE® Step 1 questions

0 / 5 complete

High Yield Notes

7 pages

Flashcards

Hyperlipidemia

of complete

Questions

USMLE® Step 1 style questions USMLE

of complete

A 26-year-old man is evaluated in the emergency department for epigastric pain that began an hour ago. He reports that the pain radiates to the back and is 9 out of 10 in severity. The patient consumes a diet rich in fresh fruits and vegetables. He drinks 2-3 glasses of wine per week on social occasions. Family history is notable for recurrent episodes of pancreatitis in his father and paternal uncle. His temperature is 37.7°C (99.9°F), blood pressure is 125/83 mmHg, and pulse is 96/min. Physical examination is notable for tenderness on light palpation of the epigastric region. Abdominal exam also reveals hepatosplenomegaly and the following finding:  


Reproduced from: Wikimedia Commons  

Xanthomas are found on the patient’s bilateral elbows. Which of the following set of laboratory findings would be most likely expected in this patient?  

External References

First Aid

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Angina

glycoprotein IIb/IIa inhibitors for p. 445

Bleeding

glycoprotein IIb/IIa inhibitors p. 445

Corneal arcus

hyperlipidemia p. 307

Glycoprotein IIb/IIa inhibitors p. 445

Hyperlipidemia p. 307

atherosclerosis and p. 308

atypical antipsychotics p. 597

glomerular filtration barrier and p. 605

immunosuppressants p. 118

nephrotic syndrome p. 619

thiazides p. 633

Skin lesions

hyperlipidemia signs p. 307

Thrombocytopenia p. 415

glycoprotein IIb/IIa inhibitors as cause p. 445

Xanthomas

hyperlipidemia and p. 307

External Links

Summary

Hyperlipidemia is a condition where you have high levels of lipids in your blood, specifically above 200 mg/dL of triglycerides and above 190 mg/dL of cholesterol. Among the causes of hyperlipidemia are genetic predisposition, high-fat diet, and sedentary lifestyle. There are also secondary causes like diabetes mellitus, metabolic disorders such as hypothyroidism. Hyperlipidemia can lead to cardiovascular and cerebrovascular diseases such as myocardial infarction and stroke.

Elsevier

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