Hypertriglyceridemia

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High Yield Notes

7 pages

Questions

USMLE® Step 1 style questions USMLE

of complete

A 26-year-old man is evaluated in the emergency department for epigastric pain that began an hour ago. He reports that the pain radiates to the back and is 9 out of 10 in severity. The patient consumes a diet rich in fresh fruits and vegetables. He drinks 2-3 glasses of wine per week on social occasions. Family history is notable for recurrent episodes of pancreatitis in his father and paternal uncle. His temperature is 37.7°C (99.9°F), blood pressure is 125/83 mmHg, and pulse is 96/min. Physical examination is notable for tenderness on light palpation of the epigastric region. Abdominal exam also reveals hepatosplenomegaly and the following finding:  


Reproduced from: Wikimedia Commons  

Xanthomas are found on the patient’s bilateral elbows. Which of the following set of laboratory findings would be most likely expected in this patient?  

Summary

Hypertriglyceridemia is a condition characterized by high levels of triglycerides in the blood. If individuals' serum triglyceride concentrations are above 150 mg/dL, they are considered hypertriglyceridemia. High levels of triglycerides in the blood are associated with a high risk of developing heart disease, stroke, and other health problems. There are many different causes of hypertriglyceridemia, including genetics, obesity, eating too much processed or unhealthy foods, not getting enough exercise, smoking cigarettes, and drinking alcohol.

Sources

  1. "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
  2. "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
  3. "Yen & Jaffe's Reproductive Endocrinology" Saunders W.B. (2018)
  4. "Bates' Guide to Physical Examination and History Taking" LWW (2016)
  5. "Robbins Basic Pathology" Elsevier (2017)
  6. "Hypertriglyceridemia: its etiology, effects and treatment" Canadian Medical Association Journal (2007)
  7. "Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline" The Journal of Clinical Endocrinology & Metabolism (2012)
  8. "Hypertriglyceridemic Pancreatitis: Presentation and Management" The American Journal of Gastroenterology (2009)
Elsevier

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