Klebsiella pneumoniae
4,505views
00:00 / 00:00
Videos
Notes
Klebsiella pneumoniae
Bacteriology
Introduction to bacteria
Bacterial structure and functions
Gram positive bacteria
Staphylococcus epidermidis
Staphylococcus aureus
Staphylococcus saprophyticus
Streptococcus viridans
Streptococcus pneumoniae
Streptococcus pyogenes (Group A Strep)
Streptococcus agalactiae (Group B Strep)
Enterococcus
Clostridium perfringens
Clostridium botulinum (Botulism)
Clostridium difficile (Pseudomembranous colitis)
Clostridium tetani (Tetanus)
Bacillus cereus (Food poisoning)
Listeria monocytogenes
Corynebacterium diphtheriae (Diphtheria)
Bacillus anthracis (Anthrax)
Nocardia
Actinomyces israelii
Gram negative bacteria
Escherichia coli
Salmonella (non-typhoidal)
Salmonella typhi (typhoid fever)
Pseudomonas aeruginosa
Enterobacter
Klebsiella pneumoniae
Shigella
Proteus mirabilis
Yersinia enterocolitica
Legionella pneumophila (Legionnaires disease and Pontiac fever)
Serratia marcescens
Bacteroides fragilis
Yersinia pestis (Plague)
Vibrio cholerae (Cholera)
Helicobacter pylori
Campylobacter jejuni
Neisseria meningitidis
Neisseria gonorrhoeae
Moraxella catarrhalis
Francisella tularensis (Tularemia)
Bordetella pertussis (Pertussis/Whooping cough)
Brucella
Haemophilus influenzae
Haemophilus ducreyi (Chancroid)
Pasteurella multocida
Mycobacteria
Mycobacterium tuberculosis (Tuberculosis)
Mycobacterium leprae
Mycobacterium avium complex (NORD)
Other bacteria
Mycoplasma pneumoniae
Chlamydia pneumoniae
Chlamydia trachomatis
Borrelia burgdorferi (Lyme disease)
Borrelia species (Relapsing fever)
Leptospira
Treponema pallidum (Syphilis)
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Coxiella burnetii (Q fever)
Ehrlichia and Anaplasma
Gardnerella vaginalis (Bacterial vaginosis)
Assessments
Klebsiella pneumoniae
Flashcards
0 / 10 complete
USMLE® Step 1 questions
0 / 2 complete
Flashcards
Klebsiella pneumoniae
of complete
Questions
USMLE® Step 1 style questions USMLE
of complete
Memory Anchors and Partner Content
External References
First Aid
2022
2021
2020
2019
2018
2017
2016
Alcoholism p. 595
Klebsiella in p. 143
Aspiration pneumonia
Klebsiella p. , 143
“Currant jelly” sputum
Klebsiella spp. p. 183
Currant jelly sputum p. 143, 183
Klebsiella pneumonia p. 716
Diabetes mellitus p. 352-360
Klebsiella p. , 143
Klebsiella spp. p. 143
alcoholism p. 176
currant jelly sputum p. 143, 183
Gram-negative algorithm p. 139
kidney stones p. 628
lactose fermentation p. 142
nosocomial infections p. 182
pneumonia p. NaN
taxonomy p. 122
urease-positive p. 125
urinary tract infections p. 625
Klebsiella pneumoniae
cephalosporins p. 186
encapsulation p. 125
immunodeficient patients p. 116
presentation p. 716
splenic dysfunction p. 96
UTIs caused by p. 179
Nosocomial infections p. 182, 280
Klebsiella p. , 143
Pneumonia p. 707
Klebsiella pneumoniae p. , 716
Urinary tract infections (UTIs) p. 179, 625
Klebsiella as cause p. 143
External Links
Transcript
Content Reviewers
Rishi Desai, MD, MPHContributors
Alexandru Duhaniuc, MD
Kaylee Neff
Klebsiella pneumoniae is a Gram-negative rod-shaped bacteria, which belongs to a family of bacteria called the Enterobacteriaceae.
Klebsiella pneumoniae can normally colonize the oropharynx and the gastrointestinal tract.
It causes various hospital-acquired infections, such as pneumonia (hence the name) and is the third most common cause of urinary tract infections.
Characteristics
Now, Klebsiella pneumoniae has a thin peptidoglycan layer, so like other Gram-negative bacteria, it stains pink.
And since it’s a bacillus, it looks like a little pink rod under the microscope.
Klebsiella pneumoniae is non-motile, non-spore forming, and facultative anaerobe.
This means it can live even without oxygen, although it grows better in an aerobic environment.
So, it prefers places like lungs,throat, or respiratory airways, as well as ventilators in the ICU where there is an unlimited flow of oxygen.
Alright, now Klebsiella pneumoniae is urease positive, which means it can produce an enzyme called urease that dissociates urea into carbon dioxide and ammonia.
This can be tested by transferring a pure sample of bacteria from the culture to a sterile tube containing a mixture of “urea agar” broth and phenol red.
Then, the mixture is incubated.
So, with Klebsiella, urease makes urea dissociate into carbon dioxide and ammonia.
Ammonia then makes the mixture change color from orange-yellow to bright pink.
Finally, Klebsiella pneumoniae grows well on MacConkey agar, which is a medium that contains a pH sensitive dye and lactose.
This medium helps identify whether Gram-negative bacteria are lactose fermenters or not.
Some Enterobacteriaceae like Klebsiella, Enterobacter, and Escherichia coli, can ferment lactose.
Summary
Klebsiella pneumoniae is a gram-negative, non-spore-forming, rod-shaped bacterium that is known to cause diseases in humans such as pneumonia, meningitis, septicemia, and urinary tract infections. Klebsiella pneumoniae is a facultative anaerobe, and lactose-fermenter, and is also able to produce an enzyme known as beta-lactamase, which makes it resistant to several antibiotics.
Copyright © 2023 Elsevier, except certain content provided by third parties
Cookies are used by this site.
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.
