Lead poisoning




Lead poisoning



Iron deficiency anemia



Sideroblastic anemia

Anemia of chronic disease

Lead poisoning

Hemolytic disease of the newborn

Glucose-6-phosphate dehydrogenase (G6PD) deficiency

Autoimmune hemolytic anemia

Pyruvate kinase deficiency

Paroxysmal nocturnal hemoglobinuria

Sickle cell disease (NORD)

Hereditary spherocytosis

Anemia of chronic disease

Aplastic anemia

Fanconi anemia

Megaloblastic anemia

Folate (Vitamin B9) deficiency

Vitamin B12 deficiency

Fanconi anemia

Diamond-Blackfan anemia

Heme synthesis disorders

Acute intermittent porphyria

Porphyria cutanea tarda

Lead poisoning

Coagulation disorders


Vitamin K deficiency

Platelet disorders

Bernard-Soulier syndrome

Glanzmann's thrombasthenia

Hemolytic-uremic syndrome

Immune thrombocytopenic purpura

Thrombotic thrombocytopenic purpura

Mixed platelet and coagulation disorders

Von Willebrand disease

Disseminated intravascular coagulation

Heparin-induced thrombocytopenia

Thrombosis syndromes (hypercoagulability)

Antithrombin III deficiency

Factor V Leiden

Protein C deficiency

Protein S deficiency

Antiphospholipid syndrome


Hodgkin lymphoma

Non-Hodgkin lymphoma


Chronic leukemia

Acute leukemia

Leukemoid reaction

Leukemoid reaction

Dysplastic and proliferative disorders

Myelodysplastic syndromes

Polycythemia vera (NORD)

Myelofibrosis (NORD)

Essential thrombocythemia (NORD)

Langerhans cell histiocytosis

Mastocytosis (NORD)

Plasma cell dyscrasias

Multiple myeloma

Monoclonal gammopathy of undetermined significance

Waldenstrom macroglobulinemia

Hematological system pathology review

Microcytic anemia: Pathology review

Non-hemolytic normocytic anemia: Pathology review

Intrinsic hemolytic normocytic anemia: Pathology review

Extrinsic hemolytic normocytic anemia: Pathology review

Macrocytic anemia: Pathology review

Heme synthesis disorders: Pathology review

Coagulation disorders: Pathology review

Platelet disorders: Pathology review

Mixed platelet and coagulation disorders: Pathology review

Thrombosis syndromes (hypercoagulability): Pathology review

Lymphomas: Pathology review

Leukemias: Pathology review

Plasma cell disorders: Pathology review

Myeloproliferative disorders: Pathology review


Lead poisoning


0 / 16 complete

USMLE® Step 1 questions

0 / 4 complete

High Yield Notes

6 pages


Lead poisoning

of complete


USMLE® Step 1 style questions USMLE

of complete

A 47-year-old man is brought to the office by his son due to increased forgetfulness and fatigue for the past three months. He has also been frequently stumbling and experienced several near-falls while climbing stairs. Review of systems is also notable for abdominal pain and numbness in the patient’s hands and feet. Past medical history is unremarkable, and he does not take any medications. He has been working as an automobile mechanic for the last 20 years. Vitals are within normal limits. The abdomen is soft, nontender, and without organomegaly on physical examination. Neurological examination reveals weakness and reduced pinprick sensation in the bilateral hands and feet. Upper and lower limb reflexes are 2/5. Laboratory testing is shown below. Which of the following is the most likely diagnosis?


External References

First Aid








Abdominal colic

lead poisoning p. 427

Basophilic stippling p. 424, 721

lead poisoning p. 427

Burton line

lead poisoning p. 427


lead poisoning p. 427


lead poisoning (adult) p. 432


for lead poisoning p. 249, 427


lead poisoning p. 427

Foot drop p. 460

lead poisoning p. 427

Headache p. 536

lead poisoning p. 432

Lead poisoning p. 427, 432

acute tubular necrosis p. 626

in anemia taxonomy p. 425

basophilic stippling in p. 424

labs/findings p. 721

presentation p. 718

sideroblastic anemia p. 427

treatment p. 249

Memory loss

lead poisoning p. 432


for lead poisoning p. 249

Sideroblastic anemia p. 424, 427

lead poisoning p. 427


lead poisoning p. 427

Wrist drop

lead poisoning p. 427


Lead poisoning is a medical condition caused by accumulation of lead in the body. Lead is a toxin that can accumulate in the body and damage almost every organ and system. Early symptoms of lead poisoning include irritability, difficulty sleeping, and loss of appetite. As the level of lead in the blood increases, more serious symptoms develop, including abdominal pain, vomiting, seizures, and coma.


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