Lymphocytic choriomeningitis virus

Lymphocytic choriomeningitis virus (LCMV) is a highly pathogenic single-stranded RNA virus that belongs to the family Arenaviridae. LCMV is mainly spread through contact with infected rodent excreta, and can also be spread through inhalation of aerosols, ingestion of contaminated food or water, or bites from infected mosquitoes or ticks.

Infection with LCMV typically causes a self-limited febrile illness, but can also lead to meningoencephalitis, hepatitis, myocarditis, and pneumonitis. In pregnant women, LCMV infection can lead to congenital malformations in the fetus or to miscarriage.