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Measuring cardiac output (Fick principle)
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Another way to calculate cardiac output is by using the Fick Principle, which simply states that at rest, the oxygen going into an organ minus the oxygen left out of an organ must equal how much oxygen that organ has used.
Both methods render normal cardiac output to around 5 litres per minute on average.
There’s a moment when the left ventricle is fully relaxed.
It occurs at the end of filling or diastole, also called the end-diastolic point, and the volume of blood within the left ventricle is called the end-diastolic volume, and it’s about 120 milliliters.
The Fick principle is a mathematical equation that calculates cardiac output by multiplying the difference between arterial and venous oxygen partial pressures by the blood flow through the vascular bed. In other words, it takes into account how much oxygen is being delivered to and removed from the tissues. This makes it a more accurate measure of cardiac output than simply measuring heart rate or blood pressure.
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