Meconium aspiration syndrome

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Summary of Meconium aspiration syndrome

Meconium aspiration syndrome is a medical condition affecting newborn infants. It occurs when meconium is present in their lungs during or before delivery. Infants who have inhaled meconium may develop respiratory distress syndrome often requiring ventilatory support.

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Meconium aspiration syndrome

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NOTES NOTES PERINATAL ACUTE RESPIRATORY DISEASE GENERALLY, WHAT IS IT? PATHOLOGY & CAUSES ▪ Respiratory problems in newborns/infants; dyspnea to sudden death SIGNS & SYMPTOMS ▪ Respiratory distress ▫ Cyanosis, bradypnea, tachypnea, etc. OTHER DIAGNOSTICS ▪ Pulse oximetry, arterial blood gases ECG ▪ Congenital heart defects TREATMENT OTHER INTERVENTIONS ▪ Supplemental oxygen therapy, assisted ventilation DIAGNOSIS DIAGNOSTIC IMAGING Chest X-ray MECONIUM ASPIRATION SYNDROME (MAS) osms.it/meconium-aspiration-syndrome PATHOLOGY & CAUSES ▪ Respiratory condition caused by aspiration of amniotic ﬂuid contaminated by meconium (fetal stool) before/during birth ▪ Bile pigments ▫ Meconium with black-green color ▪ MAS in approx. 10% of neonates exposed to meconium ▪ Meconium in airways ▫ Airway obstruction: atelectasis ▫ Surfactant deactivation, synthesis inhibition ▫ Chemical pneumonitis: irritates air pathways ▫ Persistent pulmonary hypertension of newborn (PPHN): hypertrophy of pulmonary vessels due to chronic distress ▫ Medium for bacterial growth + reduces antibacterial activity → increases risk of infection OSMOSIS.ORG 899

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Meconium aspiration syndrome

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USMLE® Step 1 style questions USMLE

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USMLE® Step 2 style questions USMLE

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A girl is born, at term, to a G2P1 30-year-old woman. Apgar scores were 6 and 8 at 1 and 5 minutes, respectively. The pregnancy and delivery were uncomplicated, but the amniotic fluid appeared brown. Now, at 10 minutes of life, she develops tachypnea and her chest is barrel-shaped. Chest X-ray reveals diffuse, patchy infiltrates and flattened diaphragms. In addition to supplemental oxygen, which of the following is the appropriate management course?

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