Megaloblastic anemia
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Megaloblastic anemia
Hematological system
Anemias
Iron deficiency anemia
Beta-thalassemia
Alpha-thalassemia
Sideroblastic anemia
Anemia of chronic disease
Lead poisoning
Hemolytic disease of the newborn
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
Autoimmune hemolytic anemia
Pyruvate kinase deficiency
Paroxysmal nocturnal hemoglobinuria
Sickle cell disease (NORD)
Hereditary spherocytosis
Anemia of chronic disease
Aplastic anemia
Fanconi anemia
Megaloblastic anemia
Folate (Vitamin B9) deficiency
Vitamin B12 deficiency
Fanconi anemia
Diamond-Blackfan anemia
Heme synthesis disorders
Acute intermittent porphyria
Porphyria cutanea tarda
Lead poisoning
Coagulation disorders
Hemophilia
Vitamin K deficiency
Platelet disorders
Bernard-Soulier syndrome
Glanzmann's thrombasthenia
Hemolytic-uremic syndrome
Immune thrombocytopenic purpura
Thrombotic thrombocytopenic purpura
Mixed platelet and coagulation disorders
Von Willebrand disease
Disseminated intravascular coagulation
Heparin-induced thrombocytopenia
Thrombosis syndromes (hypercoagulability)
Antithrombin III deficiency
Factor V Leiden
Protein C deficiency
Protein S deficiency
Antiphospholipid syndrome
Lymphomas
Hodgkin lymphoma
Non-Hodgkin lymphoma
Leukemias
Chronic leukemia
Acute leukemia
Leukemoid reaction
Leukemoid reaction
Dysplastic and proliferative disorders
Myelodysplastic syndromes
Polycythemia vera (NORD)
Myelofibrosis (NORD)
Essential thrombocythemia (NORD)
Langerhans cell histiocytosis
Mastocytosis (NORD)
Plasma cell dyscrasias
Multiple myeloma
Monoclonal gammopathy of undetermined significance
Waldenstrom macroglobulinemia
Hematological system pathology review
Microcytic anemia: Pathology review
Non-hemolytic normocytic anemia: Pathology review
Intrinsic hemolytic normocytic anemia: Pathology review
Extrinsic hemolytic normocytic anemia: Pathology review
Macrocytic anemia: Pathology review
Heme synthesis disorders: Pathology review
Coagulation disorders: Pathology review
Platelet disorders: Pathology review
Mixed platelet and coagulation disorders: Pathology review
Thrombosis syndromes (hypercoagulability): Pathology review
Lymphomas: Pathology review
Leukemias: Pathology review
Plasma cell disorders: Pathology review
Myeloproliferative disorders: Pathology review
Assessments
Megaloblastic anemia
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USMLE® Step 1 questions
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Megaloblastic anemia
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Glossitis
megaloblastic anemia p. 428
Megaloblastic anemia p. 425, 428
cytarabine p. 448
Diphyllobothrium latum p. , 157
as drug reaction p. 251
macro-ovalocytes in p. 423
orotic aciduria p. 428
trimethroprim p. 191
tropical sprue p. 390
vitamin BNaN deficiency p. 66
vitamin BNaN deficiency p. 67
Methotrexate p. 446
megaloblastic anemia p. 251
Neutrophils p. 414
megaloblastic anemia p. 428
nonmegaloblastic anemia p. 428
Phenytoin
megaloblastic anemia p. 251
Sulfa drugs p. 253
megaloblastic p. 251
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Summary
Megaloblastic anemia is a type of anemia caused by deficiencies in folic acid (folate) or vitamin B12. Folic acid and vitamin B12 are essential for DNA synthesis, and thus the production of healthy red blood cells. Megaloblastic anemia is characterized by large, nucleated red blood cell precursors which don't divide and produce more red blood cells as normal precursor cells do. Symptoms include fatigue, shortness of breath, and pale skin.
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