Neonatal hepatitis is a type of liver inflammation that affects newborn babies. It may be caused by a viral infection, such as rubella, cytomegalovirus, and hepatitis viruses A, B, and C. In some cases, the cause may be a problem with the baby's liver (e.g. alpha-1 antitrypsin deficiency), or even unknown sometimes (idiopathic).
Symptoms of neonatal hepatitis may include jaundice (yellowing of the skin and whites of the eyes), dark urine, light stools, swelling of the abdomen, and failure to grow and gain weight at the expected rate. The severity of the symptoms can vary depending on the cause and severity of hepatitis.
Treatment for neonatal hepatitis may include medications to control the inflammation and support the functioning of the liver, as well as supportive care, such as fluid and electrolyte management. In severe cases, a liver transplant may be necessary.
- "Robbins Basic Pathology" Elsevier (2017)
- "Harrison's Principles of Internal Medicine" McGraw Hill / Medical (2018)
- "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
- "CURRENT Medical Diagnosis and Treatment 2020" McGraw Hill Professional (2019)
- "Neonatal hemochromatosis: A rare cause of liver failure in infancy" Indian Journal of Pathology and Microbiology (2020)
- "Neonatal hepatitis syndrome" Seminars in Neonatology (2003)