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Neonatal sepsis

Summary of Neonatal sepsis
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. It is divided into two categories: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis presenting in the first 3 days of life, and is usually caused by Group B Streptococci or Escherichia coli. It presents with pneumonia. LOS is the presentation of sepsis after 3 days, and is usually caused by Staphylococcus. It presents with meningitis. The treatment depends on the underlying etiology.

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Neonatal sepsis

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High Yield Notes
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Neonatal sepsis

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USMLE® Step 1 style questions USMLE

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USMLE® Step 2 style questions USMLE

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Preview

A 10-day old male infant comes to the emergency department because he has had 5 episodes of non-bloody, non-billious emesis. Two days ago, he began having difficulty feeding and was sleepier and fussier than usual. Physical exam shows that his face, neck, and chest are jaundiced. He appears lethargic with decreased muscle tone and full range of neck motion. His temperature is 35°C (95°F), pulse 155/minute, respirations 38/minute, and blood pressure 80/49 mm Hg. Which of the following is the most appropriate next step inmanagement?