Neonatal sepsis
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Neonatal sepsis
Immune system
General infections
Sepsis
Neonatal sepsis
Abscesses
Hypersensitivity reactions
Type I hypersensitivity
Food allergy
Anaphylaxis
Asthma
Type II hypersensitivity
Immune thrombocytopenic purpura
Autoimmune hemolytic anemia
Hemolytic disease of the newborn
Goodpasture syndrome
Rheumatic heart disease
Myasthenia gravis
Graves disease
Pemphigus vulgaris
Type III hypersensitivity
Serum sickness
Systemic lupus erythematosus
Poststreptococcal glomerulonephritis
Type IV hypersensitivity
Graft-versus-host disease
Contact dermatitis
Transplants
Transplant rejection
Graft-versus-host disease
Cytomegalovirus infection after transplant (NORD)
Post-transplant lymphoproliferative disorders (NORD)
Immunodeficiences
X-linked agammaglobulinemia
Selective immunoglobulin A deficiency
Common variable immunodeficiency
IgG subclass deficiency
Hyperimmunoglobulin E syndrome
Isolated primary immunoglobulin M deficiency
Thymic aplasia
DiGeorge syndrome
Severe combined immunodeficiency
Adenosine deaminase deficiency
Ataxia-telangiectasia
Hyper IgM syndrome
Wiskott-Aldrich syndrome
Leukocyte adhesion deficiency
Chediak-Higashi syndrome
Chronic granulomatous disease
Complement deficiency
Hereditary angioedema
Asplenia
Immune system organ disorders
Thymoma
Ruptured spleen
Immune system pathology review
Blood transfusion reactions and transplant rejection: Pathology review
Immunodeficiencies: T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review
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Neonatal sepsis
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Neonatal sepsis
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Summary
Neonatal sepsis is a serious condition in which bacteria and other germs enter the body and cause an infection in a neonate's bloodstream, in the setting of fever. Neonatal sepsis has two categories: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis presenting in the first 3 days of life. EOS is usually caused by Group B Streptococci or Escherichia coli, usually presenting itself as pneumonia. On the other hand, LOS presents itself after 3 days. LOS is usually caused by Staphylococcus and commonly manifests itself as meningitis.
Symptoms of neonatal sepsis may depend on the category, but they commonly include fever, irritability, difficulty feeding, and a poor overall appearance. In severe cases, neonatal sepsis can lead to organ failure and death.
Treatment for neonatal sepsis typically involves antibiotics to kill the bacteria causing the infection and supportive care, such as intravenous fluids, respiratory support, and medications to control symptoms like fever.
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