Neuroleptic malignant syndrome

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Neuroleptic malignant syndrome

Nervous system and special senses

Adverse effects of drugs on the nervous system

Neuroleptic malignant syndrome
Serotonin syndrome

Cerebrovascular disease

Broca aphasia
Kluver-Bucy syndrome
Wernicke aphasia
Epidural hematoma
Intracerebral hemorrhage
Saccular aneurysm
Subarachnoid hemorrhage
Subdural hematoma
Ischemic stroke
Transient ischemic attack
Arteriovenous malformation
Cavernous sinus thrombosis
Subclavian steal syndrome
Vascular dementia

Congenital disorders

Aqueductal stenosis
Cerebral palsy
Chiari malformation
Dandy-Walker malformation
Friedreich ataxia
Neurofibromatosis
Septo-optic dysplasia
Spina bifida
Spinocerebellar ataxia (NORD)
Sturge-Weber syndrome
Tethered spinal cord syndrome
Tuberous sclerosis
von Hippel-Lindau disease

Cranial and peripheral nerve disorders

Bell palsy
Horner syndrome
Carpal tunnel syndrome
Charcot-Marie-Tooth disease
Erb-Duchenne palsy
Guillain-Barre syndrome
Klumpke paralysis
Sciatica
Thoracic outlet syndrome
Ulnar claw
Winged scapula

Degenerative disorders or amnesic syndromes

Alzheimer disease
Creutzfeldt-Jakob disease
Dementia with Lewy bodies
Frontotemporal dementia
Normal pressure hydrocephalus
Vascular dementia

Demyelinating disorders

Acute disseminated encephalomyelitis
Central pontine myelinolysis
JC virus (Progressive multifocal leukoencephalopathy)
Multiple sclerosis
Transverse myelitis
Charcot-Marie-Tooth disease
Guillain-Barre syndrome

Disorders relating to the spine, spinal cord, and spinal nerve roots

Brown-Sequard Syndrome
Cauda equina syndrome
Friedreich ataxia
Neurogenic bladder
Syringomyelia
Treponema pallidum (Syphilis)
Vitamin B12 deficiency

Global cerebral dysfunction

Delirium

Infectious, immunologic, and inflammatory disorders

Acute disseminated encephalomyelitis
Multiple sclerosis
Myasthenia gravis
Thymoma
Transverse myelitis
Brain abscess
Creutzfeldt-Jakob disease
Encephalitis
Epidural abscess
Meningitis
Neonatal meningitis

Metabolic disorders

Adrenoleukodystrophy (NORD)

Movement disorders

Essential tremor
Huntington disease
Opsoclonus myoclonus syndrome (NORD)
Parkinson disease
Restless legs syndrome
Torticollis

Neoplasms

Adult brain tumors
Neurofibromatosis
Pediatric brain tumors
Pituitary adenoma

Neurologic pain syndromes

Fibromyalgia
Trigeminal neuralgia

Neuromuscular disorders

Amyotrophic lateral sclerosis
Lambert-Eaton myasthenic syndrome
Muscular dystrophy
Myasthenia gravis
Myotonic dystrophy
Spinal muscular atrophy

Paroxysmal disorders

Cavernous sinus thrombosis
Cluster headache
Idiopathic intracranial hypertension
Migraine
Tension headache
Trigeminal neuralgia
Early infantile epileptic encephalopathy (NORD)
Febrile seizure
Seizures and epilepsy

Sleep disorders

Insomnia
Narcolepsy (NORD)
Night terrors
Restless legs syndrome

Traumatic and mechanical disorders and disorders of increased intracranial pressure

Brain herniation
Concussion and traumatic brain injury
Epidural hematoma
Idiopathic intracranial hypertension
Intracerebral hemorrhage
Normal pressure hydrocephalus
Subarachnoid hemorrhage
Subdural hematoma

Disorders of the ear

Acoustic neuroma (schwannoma)
Labyrinthitis
Meniere disease
Vertigo
Conductive hearing loss
Otitis externa
Otitis media
Acoustic neuroma (schwannoma)
Neurofibromatosis
Eustachian tube dysfunction
Tympanic membrane perforation

Disorders of the eye and eyelid

Cataract
Glaucoma
Age-related macular degeneration
Color blindness
Diabetic retinopathy
Retinal detachment
Retinopathy of prematurity
Conjunctivitis
Corneal ulcer
Hordeolum (stye)
Keratitis
Neonatal conjunctivitis
Orbital cellulitis
Periorbital cellulitis
Uveitis
Retinoblastoma
Bitemporal hemianopsia
Cortical blindness
Hemianopsia
Homonymous hemianopsia

Nervous system and special senses pathology review

Psychiatric emergencies: Pathology review
Cerebral vascular disease: Pathology review
Congenital neurological disorders: Pathology review
Neurocutaneous disorders: Pathology review
Dementia: Pathology review
Amnesia, dissociative disorders and delirium: Pathology review
Eye conditions: Inflammation, infections and trauma: Pathology review
Eye conditions: Refractive errors, lens disorders and glaucoma: Pathology review
Eye conditions: Retinal disorders: Pathology review
Vertigo: Pathology review
Spinal cord disorders: Pathology review
Central nervous system infections: Pathology review
Demyelinating disorders: Pathology review
Peroxisomal disorders: Pathology review
Movement disorders: Pathology review
Adult brain tumors: Pathology review
Pediatric brain tumors: Pathology review
Muscular dystrophies and mitochondrial myopathies: Pathology review
Neuromuscular junction disorders: Pathology review
Headaches: Pathology review
Seizures: Pathology review
Psychological sleep disorders: Pathology review
Traumatic brain injury: Pathology review

Key Takeaways

Neuroleptic malignant syndrome is a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs, which are used to treat mental health conditions, such as schizophrenia, bipolar disorder, and severe depression. Neuroleptic malignant syndrome typically presents with muscle rigidity, fever, autonomic instability, and cognitive changes such as delirium.