Neuroleptic malignant syndrome

High Yield Notes

10 pages

Flashcards

Neuroleptic malignant syndrome

of complete

Questions

USMLE® Step 1 style questions USMLE

of complete

A 23-year-old man is brought to the emergency department after collapsing at a music festival on a hot summer day. The patient was with friends at an electronic dance show. According to his friends, the patient consumed a powdered drug at the concert. Afterwards, while dancing, he suddenly collapsed and started having tremors in the upper and lower extremities. He has a past medical history of depression, anxiety, and bipolar disorder, for which he takes fluoxetine, alprazolam as needed, and aripiprazole. Temperature is 39.0°C (102.2 °F), pulse is 132/min, respirations are 24/min, blood pressure is 172/85 mmHg, and O2 saturation is 97% on room air. On physical examination the patient is diaphoretic, mumbling incoherent sounds, and will not lie still in the gurney. The patient has increased muscle tone. Brief, sudden jerks are present throughout the upper and lower extremities. Which of the following clinical features is most specific to this patient's clinical presentation?

External References

First Aid

2024

2023

2022

2021

Fever

neuroleptic malignant syndrome p. 587

Neuroleptic malignant syndrome (NMS) p. 567, 587

Summary

Neuroleptic malignant syndrome is a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs, which are used to treat mental health conditions, such as schizophrenia, bipolar disorder, and severe depression. Neuroleptic malignant syndrome typically presents with muscle rigidity, fever, autonomic instability, and cognitive changes such as delirium.

Elsevier

Copyright © 2024 Elsevier, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

Cookies are used by this site.

USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.

RELX