Osteogenesis imperfecta
Videos
Notes
Osteogenesis imperfecta
Musculoskeletal system
Musculoskeletal system
Musculoskeletal system
Musculoskeletal system
Assessments
Osteogenesis imperfecta
Flashcards
0 / 11 complete
USMLE® Step 1 questions
0 / 3 complete
High Yield Notes
16 pages
Flashcards
Osteogenesis imperfecta
of complete
Questions
USMLE® Step 1 style questions USMLE
of complete
Image reproduced from Wikimedia Commons
Laboratory results are within normal limits. Plain radiograph shows a fracture of the olecranon. Which of the following is the most likely explanation for the patient’s presentation?
Memory Anchors and Partner Content
External References
First Aid
2022
2021
2020
2019
2018
2017
2016
Bisphosphonates p. 499
osteogenesis imperfecta treatment p. 49
Blue sclerae p. 49
osteogenesis imperfecta p. 714
Bone disorders
osteogenesis imperfecta p. 49
Child abuse p. 579
osteogenesis imperfecta and p. 49
Dentin
osteogenesis imperfecta p. 49
Hearing loss p. 552
osteogenesis imperfecta p. 49
Osteogenesis imperfecta p. 49
bisphosphonates p. 499
collagen and p. 48
presentation p. 714
Sclerae p. 553
osteogenesis imperfecta p. 49
Teeth
osteogenesis imperfecta p. 49
External Links
Summary
Osteogenesis imperfecta (OI) is a genetic bone disorder characterized by impaired production of type 1 collagen, an essential protein in the development and maintenance of bones and connective tissue. Collagen provides strength and support to the bones, and in individuals with OI, the collagen produced is weak, leading to bones that are brittle and prone to fractures.
OI may present with shorter height and neurological features, including communicating hydrocephalus, basilar invagination, seizures, blue sclerae, hearing loss, and other complications. Associated fractures may cause acute or chronic pain, reduced quality of life, and depression.
For Institutions
Copyright © 2023 Elsevier, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
Cookies are used by this site.
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.
