00:00 / 00:00
Endocrine system anatomy and physiology
Hunger and satiety
Growth hormone and somatostatin
Oxytocin and prolactin
Synthesis of adrenocortical hormones
Estrogen and progesterone
Phosphate, calcium and magnesium homeostasis
Oxytocin and prolactin
0 / 6 complete
oxytocin p. 652
oxytocin for induction of p. 364
oxytocin for p. 364
functions of p. 335
hypothalamic/pituitary drugs p. 364
hypothalamus production p. 511
lactation and p. 652
pituitary gland and p. 339
signaling pathways for p. 353
Sam Gillespie, BSc
Oxytocin and prolactin are two hormones that are mostly involved in the production and release of milk from the breasts during the nursing period. Prolactin - pro meaning “for” and “lactin” referring to milk - it stimulates the production of milk.
Oxytocin, on the other hand, makes the smooth muscle cells around the glands in the breasts contract so that they release the milk.
Oxytocin also helps the muscle in the uterus contract during labor. Both of these hormones are synthesized all the way up in the brain, by two interconnected structures – the hypothalamus and the pituitary gland.
So, basically, the hypothalamus is a part of the brain made up of several nuclei – or clusters of neurons.
Two of these nuclei, the paraventricular and supraoptic nuclei, contain neurons that secrete oxytocin, as well as other hormones like vasopressin, or antidiuretic hormone, which is involved in regulating the amount of water in our body.
When oxytocin is produced, it travels down the axons of these neurons, and reaches the posterior lobe of the pituitary gland.
Down the length of these axons, there are small dilations called Herring bodies – which store the oxytocin until it’s released in the blood.
Outside of pregnancy, oxytocin levels are low, but production increases just a bit during an orgasm - so here’s the reason for that lovely “afterglow”.
Prolactin, on the other hand, is synthesized by special cells called lactotrophs, which are in the anterior lobe of the pituitary.
In women that are not pregnant or breastfeeding, and in men, prolactin levels are usually kept in check by the hypothalamus in two ways.
Oxytocin and prolactin are two hormones that are involved in a variety of physiological processes, including reproductive and lactation functions. During pregnancy, these hormones prepare the breasts for lactation, by stimulating the maturation of the milk-secreting alveoli.
Oxytocin is produced by the hypothalamus and released by the posterior pituitary gland. It plays a role in childbirth, lactation, and sexual behavior. It is also thought to have a role in social bonding and attachment. On the other hand, prolactin is produced by the anterior pituitary gland and plays a role in lactation and the production of breast milk. It is also involved in the regulation of the menstrual cycle and fertility.
Copyright © 2023 Elsevier, except certain content provided by third parties
Cookies are used by this site.
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.