Paget disease of the breast
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Paget disease of the breast
Reproductive system and breast
Disorders of puberty, sex chromosomes, and sex hormones
Female and transgender reproductive system and breast
Breast cancer
Fibrocystic breast changes
Intraductal papilloma
Mastitis
Paget disease of the breast
Phyllodes tumor
Turner syndrome
Endometritis
Pelvic inflammatory disease
Urethritis
Amenorrhea
Endometriosis
Polycystic ovary syndrome
Premature ovarian failure
Cervical cancer
Choriocarcinoma
Endometrial cancer
Endometrial hyperplasia
Germ cell ovarian tumor
Gestational trophoblastic disease
Krukenberg tumor
Ovarian cyst
Ovarian torsion
Sex cord-gonadal stromal tumor
Surface epithelial-stromal tumor
Uterine fibroid
Female sexual interest and arousal disorder
Genito-pelvic pain and penetration disorder
Orgasmic dysfunction
Male and transgender reproductive system
Pregnancy, childbirth, and the puerperium
Cervical incompetence
Chorioamnionitis
Ectopic pregnancy
Gestational diabetes
Gestational hypertension
Hyperemesis gravidarum
Intrauterine growth restriction
Miscarriage
Oligohydramnios
Placenta accreta
Placenta previa
Placental abruption
Polyhydramnios
Potter sequence
Preeclampsia & eclampsia
Preterm labor
Postpartum hemorrhage
Congenital cytomegalovirus (NORD)
Congenital rubella syndrome
Congenital syphilis
Congenital toxoplasmosis
Neonatal conjunctivitis
Neonatal herpes simplex
Neonatal meningitis
Neonatal sepsis
Fetal alcohol syndrome
Fetal hydantoin syndrome
Reproductive system and breast pathology review
Benign breast conditions: Pathology review
Breast cancer: Pathology review
Amenorrhea: Pathology review
Cervical cancer: Pathology review
Ovarian cysts and tumors: Pathology review
Sexually transmitted infections: Vaginitis and cervicitis: Pathology review
Uterine disorders: Pathology review
Vaginal and vulvar disorders: Pathology review
Disorders of sex chromosomes: Pathology review
Disorders of sexual development and sex hormones: Pathology review
Sexually transmitted infections: Warts and ulcers: Pathology review
Penile conditions: Pathology review
Prostate disorders and cancer: Pathology review
Testicular and scrotal conditions: Pathology review
Testicular tumors: Pathology review
Complications during pregnancy: Pathology review
Congenital TORCH infections: Pathology review
Assessments
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USMLE® Step 1 questions
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High Yield Notes
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Flashcards
Paget disease of the breast
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Questions
USMLE® Step 1 style questions USMLE
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A 50-year-old woman comes to the clinic following an abnormal mammogram showing calcifications in the right breast. Medical history is remarkable for type 2 diabetes mellitus managed with metformin. She does not smoke or use alcohol excessively, and she has not experienced weight loss, fever, or trauma. She is referred for a biopsy, which confirms the diagnosis of benign fat necrosis. However, during the biopsy, another area suspected of malignancy is found. The results of the biopsy of this additional are are shown below:
Reproduced from: flickr
This type of cancer is associated with which of the following?
Reproduced from: flickr
This type of cancer is associated with which of the following?
Summary
Paget disease of the breast (PDB) is a rare, malignant, and noninvasive variant of breast cancer, which results from underlying ductal carcinoma in situ or invasive breast cancer. Symptoms of Paget disease of the breast include unilateral redness and flakiness of the skin on the nipple and areola. There may also be itching, burning, swelling, breast tenderness, and nipple discharges. Treatment may involve surgery to remove the cancerous tissue and radiotherapy and/or chemotherapy to kill any remaining cancer cells.