Paget disease of the breast

Reproductive

Reproductive

Anatomy of the pelvic girdle
Anatomy of the pelvic cavity
Arteries and veins of the pelvis
Anatomy of the breast
Anatomy clinical correlates: Breast
Development of the reproductive system
Prostate gland histology
Penis histology
Testis, ductus deferens, and seminal vesicle histology
Mammary gland histology
Ovary histology
Fallopian tube and uterus histology
Cervix and vagina histology
Anatomy and physiology of the male reproductive system
Puberty and Tanner staging
Testosterone
Anatomy and physiology of the female reproductive system
Estrogen and progesterone
Menstrual cycle
Menopause
Pregnancy
Oxytocin and prolactin
Stages of labor
Breastfeeding
Precocious puberty
Delayed puberty
Klinefelter syndrome
Turner syndrome
Androgen insensitivity syndrome
5-alpha-reductase deficiency
Kallmann syndrome
Hypospadias and epispadias
Bladder exstrophy
Priapism
Penile cancer
Prostatitis
Benign prostatic hyperplasia
Prostate cancer
Cryptorchidism
Inguinal hernia
Varicocele
Epididymitis
Orchitis
Testicular torsion
Testicular cancer
Erectile dysfunction
Male hypoactive sexual desire disorder
Amenorrhea
Ovarian cyst
Premature ovarian failure
Polycystic ovary syndrome
Ovarian torsion
Krukenberg tumor
Sex cord-gonadal stromal tumor
Surface epithelial-stromal tumor
Germ cell ovarian tumor
Uterine fibroid
Endometriosis
Endometritis
Endometrial hyperplasia
Endometrial cancer
Choriocarcinoma
Cervical cancer
Pelvic inflammatory disease
Urethritis
Female sexual interest and arousal disorder
Orgasmic dysfunction
Genito-pelvic pain and penetration disorder
Mastitis
Fibrocystic breast changes
Intraductal papilloma
Phyllodes tumor
Paget disease of the breast
Breast cancer
Hyperemesis gravidarum
Gestational hypertension
Preeclampsia & eclampsia
Gestational diabetes
Cervical incompetence
Placenta previa
Placenta accreta
Placental abruption
Oligohydramnios
Polyhydramnios
Potter sequence
Intrauterine growth restriction
Preterm labor
Postpartum hemorrhage
Chorioamnionitis
Congenital toxoplasmosis
Congenital cytomegalovirus (NORD)
Congenital syphilis
Neonatal conjunctivitis
Neonatal herpes simplex
Congenital rubella syndrome
Neonatal sepsis
Neonatal meningitis
Miscarriage
Gestational trophoblastic disease
Ectopic pregnancy
Fetal hydantoin syndrome
Fetal alcohol syndrome
Disorders of sex chromosomes: Pathology review
Prostate disorders and cancer: Pathology review
Testicular tumors: Pathology review
Uterine disorders: Pathology review
Ovarian cysts and tumors: Pathology review
Cervical cancer: Pathology review
Vaginal and vulvar disorders: Pathology review
Benign breast conditions: Pathology review
Breast cancer: Pathology review
Complications during pregnancy: Pathology review
Congenital TORCH infections: Pathology review
Androgens and antiandrogens
PDE5 inhibitors
Adrenergic antagonists: Alpha blockers
Estrogens and antiestrogens
Progestins and antiprogestins
Aromatase inhibitors
Uterine stimulants and relaxants

Assessments

Flashcards

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USMLE® Step 1 questions

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High Yield Notes

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Flashcards

Paget disease of the breast

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Questions

USMLE® Step 1 style questions USMLE

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A 50-year-old woman comes to the clinic following an abnormal mammogram showing calcifications in the right breast. Medical history is remarkable for type 2 diabetes mellitus managed with metformin. She does not smoke or use alcohol excessively, and she has not experienced weight loss, fever, or trauma. She is referred for a biopsy, which confirms the diagnosis of benign fat necrosis. However, during the biopsy, another area suspected of malignancy is found. The results of the biopsy of this additional are are shown below:  



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This type of cancer is associated with which of the following?  

Summary

Paget disease of the breast (PDB) is a rare, malignant, and noninvasive variant of breast cancer, which results from underlying ductal carcinoma in situ or invasive breast cancer. Symptoms of Paget disease of the breast include unilateral redness and flakiness of the skin on the nipple and areola. There may also be itching, burning, swelling, breast tenderness, and nipple discharges. Treatment may involve surgery to remove the cancerous tissue and radiotherapy and/or chemotherapy to kill any remaining cancer cells.