Skip to content

Penile cancer

Summary of Penile cancer
Penile cancer is a malignant growth found on the skin or in the tissues of the penis. Around 95% of penile cancers are squamous cell carcinomas. Other types of penile cancer such as Merkel cell carcinoma, small cell carcinoma, melanoma and other are generally rare. Squamous cell carcinoma is more common in Asia, Africa, and South America. Precursor in situ lesions include: Bowen disease (in  penile shaft, presents as leukoplakia), erythroplasia of Queyrat (cancer of glans, presents as  erythroplakia), and Bowenoid papulosis (carcinoma in situ of unclear malignant potential, presenting  as reddish papules). Penile squamous cell carcinoma is associated with human papillomavirus infection and lack of circumcision.




Reproductive system

Male and female reproductive system disorders
Male reproductive system disorders
Female reproductive system disorders
Reproductive system pathology review

Penile cancer


0 / 6 complete


1 / 4 complete
High Yield Notes
7 pages

Penile cancer

6 flashcards

is the most common type of penile cancer.


USMLE® Step 1 style questions USMLE

4 questions

A 52-year-old man presents to an outpatient clinic for evaluation of an itchy rash on his penis. The rash has been present on the glans of the penis for seven weeks. The patient immigrated from Argentina in his twenties and is unsure of his vaccination status. He has had multiple sexual partners and occasionally uses condoms for protection. Physical examination reveals an uncircumcised penis. A 2-cm velvety, red, well-marginated, painless ulcer is noted on the glans penis. No other penile deformities are observed. Which of the following is the most likely diagnosis?

External References