Pharmacokinetics: Drug elimination and clearance
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Questions
USMLE® Step 1 style questions USMLE
of complete
USMLE® Step 2 style questions USMLE
of complete
A researcher attempts to understand the factors that influence the elimination rates of a commonly prescribed medication. The medication is found to have a constant elimination rate independent of plasma concentration, as demonstrated in the graph below. Which of the statements regarding this medication is most likely true?
Sources
- "Katzung & Trevor's Pharmacology Examination and Board Review,12th Edition" McGraw-Hill Education / Medical (2018)
- "Rang and Dale's Pharmacology" Elsevier (2019)
- "Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery" NeuroRX (2005)
- "Renal drug transporters and their significance in drug–drug interactions" Acta Pharmaceutica Sinica B (2016)
- "Renal Drug Transporters and Drug Interactions" Clinical Pharmacokinetics (2017)
- "Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition" McGraw-Hill Education / Medical (2017)
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