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Acute respiratory distress syndrome
Pulmonary changes at high altitude and altitude sickness
Congenital pulmonary airway malformation
Superior vena cava syndrome
Apnea of prematurity
Meconium aspiration syndrome
Neonatal respiratory distress syndrome
Sudden infant death syndrome
Transient tachypnea of the newborn
Alpha 1-antitrypsin deficiency
Idiopathic pulmonary fibrosis
Restrictive lung diseases
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Cystic fibrosis: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Lung cancer and mesothelioma: Pathology review
Obstructive lung diseases: Pathology review
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Pneumonia: Pathology review
Respiratory distress syndrome: Pathology review
Restrictive lung diseases: Pathology review
Tuberculosis: Pathology review
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with pneumothorax p. 706
pneumothorax p. 706
pneumothorax p. 705, 706
pneumothorax p. 706
With pneumothorax, pneumo refers to air and thorax means chest, so a pneumothorax is when there is air in the chest; more specifically air in the space between the lungs and chest wall – called the pleural space.
The pleural space normally contains a lubricating fluid that helps reduce friction as the lungs expand and contract.
Pressure within the pleural space is established by two main opposing forces.
One is the muscle tension of the diaphragm and chest wall which contract and expand the thoracic cavity outwards, and the other is the elastic recoil of the lungs, which try to pull the lungs inward.
The two pull on each other creating a balance between the forces that creates a slight vacuum in the pleural space.
It results in the pleural space having a pressure of -5 centimeters of water relative to the pressure of 0 centimeters of water in both the thoracic cavity and the lungs.
Since the negative pleural pressure is lost, the two opposing forces no longer pull on one another.
As a result, the lungs simply pull inwards and collapse, and the chest wall simply springs outward a bit.
A collapsed lung limits how well it can exchange air, and can lead to a reduction in oxygen being brought into the body, and a build-up of carbon dioxide in the body because it can’t easily get released.
There are many types of pneumothorax.
The first is a spontaneous pneumothorax which typically occurs when a bullae, which is an air pocket, forms on the surface of the lungs and breaks.
A pneumothorax refers to an abnormal collection of air or gas in the pleural space that causes a loss of negative pressure. Like pleural effusion (liquid buildup in that space), pneumothorax may interfere with normal breathing. Pneumothorax can either be traumatic, or spontaneous. Traumatic pneumothorax occurs due to an injury to the chest, such as a broken rib or puncture wound. On the other hand, spontaneous pneumothorax can happen without an apparent cause. It is commonly seen in patients with lung diseases such as COPD, cystic fibrosis, asthma, smokers, and people with Marfan syndrome. Symptoms of pneumothorax can include chest pain, shortness of breath, and difficulty breathing. The diagnosis is typically made with a chest X-ray or CT scan. Treatment for a pneumothorax may require a chest tube to remove the air or gas and re-expand the lung.
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