Summary of Primary myelofibrosis
Flashcards on Primary myelofibrosis
Myelofibrosis is characterized by the presence of erythrocytes in the blood smear.
Questions on Primary myelofibrosis
A 55-year-old man comes to his primary care provider's office because of fatigue for the past six months. He is a construction worker and says that he has been feeling more tired at work than usual. He had to take a half day several times in the month just to recuperate and feel better. During the same time period, he has lost 9.1-kg (20-lb). Physical examination shows splenomegaly and petechiae on his upper extremities. A peripheral blood smear shows teardrop red blood cells. A bone marrow biopsy is done and shows fibrosis of the bone marrow. Which of the following mutations is most likely associated with this patient's condition?