Prostate cancer

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Prostate cancer

Reproductive system

Male and female reproductive system disorders

Precocious puberty

Delayed puberty

Klinefelter syndrome

Turner syndrome

Androgen insensitivity syndrome

5-alpha-reductase deficiency

Kallmann syndrome

Male reproductive system disorders

Hypospadias and epispadias

Bladder exstrophy

Priapism

Penile cancer

Prostatitis

Benign prostatic hyperplasia

Prostate cancer

Cryptorchidism

Inguinal hernia

Varicocele

Epididymitis

Orchitis

Testicular torsion

Testicular cancer

Erectile dysfunction

Male hypoactive sexual desire disorder

Female reproductive system disorders

Amenorrhea

Ovarian cyst

Premature ovarian failure

Polycystic ovary syndrome

Ovarian torsion

Krukenberg tumor

Sex cord-gonadal stromal tumor

Surface epithelial-stromal tumor

Germ cell ovarian tumor

Uterine fibroid

Endometriosis

Endometritis

Endometrial hyperplasia

Endometrial cancer

Choriocarcinoma

Cervical cancer

Pelvic inflammatory disease

Urethritis

Female sexual interest and arousal disorder

Orgasmic dysfunction

Genito-pelvic pain and penetration disorder

Mastitis

Fibrocystic breast changes

Intraductal papilloma

Phyllodes tumor

Paget disease of the breast

Breast cancer

Hyperemesis gravidarum

Gestational hypertension

Preeclampsia & eclampsia

Gestational diabetes

Cervical incompetence

Placenta previa

Placenta accreta

Placental abruption

Oligohydramnios

Polyhydramnios

Potter sequence

Intrauterine growth restriction

Preterm labor

Postpartum hemorrhage

Chorioamnionitis

Congenital toxoplasmosis

Congenital cytomegalovirus (NORD)

Congenital syphilis

Neonatal conjunctivitis

Neonatal herpes simplex

Congenital rubella syndrome

Neonatal sepsis

Neonatal meningitis

Miscarriage

Gestational trophoblastic disease

Ectopic pregnancy

Fetal hydantoin syndrome

Fetal alcohol syndrome

Reproductive system pathology review

Disorders of sex chromosomes: Pathology review

Prostate disorders and cancer: Pathology review

Testicular tumors: Pathology review

Uterine disorders: Pathology review

Ovarian cysts and tumors: Pathology review

Cervical cancer: Pathology review

Vaginal and vulvar disorders: Pathology review

Benign breast conditions: Pathology review

Breast cancer: Pathology review

Complications during pregnancy: Pathology review

Congenital TORCH infections: Pathology review

Disorders of sexual development and sex hormones: Pathology review

Amenorrhea: Pathology Review

Testicular and scrotal conditions: Pathology review

Sexually transmitted infections: Warts and ulcers: Pathology review

Sexually transmitted infections: Vaginitis and cervicitis: Pathology review

HIV and AIDS: Pathology review

Penile conditions: Pathology review

Assessments

Prostate cancer

Flashcards

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USMLE® Step 1 questions

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High Yield Notes

7 pages

Flashcards

Prostate cancer

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Questions

USMLE® Step 1 style questions USMLE

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A 63-year-old man comes to the office because of nocturnal back pain that is not relieved by rest or change in position. He was diagnosed with localized prostate cancer 6 months ago and was started on long-acting gonadotropin releasing hormone (GnRH) agonist after refusal of surgical prostatectomy and radiation therapy. Further evaluation confirms the diagnosis of metastatic prostate adenocarcinoma. A decision to start flutamide is made to help relieve pain and decrease the size of the tumor. Which of the following best describes the mechanism of action of this agent?  

External References

First Aid

2022

2021

2020

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2016

Prostate cancer

adenocarcinomas p. 678

estrogens for p. 680

incidence/mortality of p. 202

leuprolide for p. 680

metastases of p. 224

tumor suppressor genes and p. 222

Transcript

Contributors

Charles Davis, MD

Evan Debevec-McKenney

Tanner Marshall, MS

Prostate cancer, usually refers to prostate adenocarcinoma, where adeno- means gland and carcinoma refers to uncontrolled growth of cells - so prostate cancer is a tumor or growth that originates in the prostate gland.

Only males are born with a prostate, so this condition only affects males and not females.

Typically, when there’s a prostate cancer it’s considered malignant, meaning that the tumor cells can metastasize, or invade and destroy surrounding tissues as well as tissues throughout the body.

The prostate is a small gland, about the size and shape of a walnut, that sits under the bladder and in front of the rectum.

The urethra which is the tube through which urine leaves the bladder, goes through the prostate before reaching the penis.

And that part of the urethra is called the prostatic urethra.

The prostate is covered by a capsule of tough connective tissue and smooth muscle.

Beneath this layer, the prostate can be divided into a few zones.

The peripheral zone, which is the outermost posterior section, is the largest of the zone and contain about 70% of the prostate’s glandular tissue.

Moving inward, the next section is the central zone which contains about 25% of the glandular tissue as well as the ejaculatory ducts that join with the prostatic urethra.

Last, is the transitional zone, which contains around 5% of the glandular tissue as well as a portion of the prostatic urethra.

Summary

Prostate cancer is a type of cancer that develops in the prostate, a gland in the male reproductive system. It usually arises in the posterior lobe of the prostate and can spread to other parts of the body, particularly the bones and lymph nodes. Symptoms include difficulty urinating, blood in the urine, weight loss, and pain in the pelvis during urination. Treatment may involve a combination of chemotherapy, radiotherapy, hormonal therapy, and surgery.

Elsevier

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