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Protein S deficiency

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Pathology

Hematological system

Anemias
Heme synthesis disorders
Coagulation disorders
Platelet disorders
Mixed platelet and coagulation disorders
Thrombosis syndromes (hypercoagulability)
Lymphomas
Leukemias
Leukemoid reaction
Dysplastic and proliferative disorders
Plasma cell dyscrasias
Hematological system pathology review

Assessments
Protein S deficiency

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High Yield Notes
6 pages
Flashcards

Protein S deficiency

9 flashcards
Preview

Protein S deficiency is inherited in an autosomal (dominant/recessive) manner.

Questions

USMLE® Step 1 style questions USMLE

1 questions

USMLE® Step 2 style questions USMLE

1 questions
Preview

 A 43-year-old woman comes to the emergency department because of sudden-onset dyspnea. Her medical history is relevant for varicose veins in lower extremities, controlled diabetes mellitus, and 30 pack-year smoking history. The patient currently takes metformin and pioglitazone. Upon further questioning, the patient mentions that her sister died at 35 because of a pulmonary embolism. Physical exam shows clammy skin and diaphoresis, S3  gallop, erythema over varicose veins in her left leg. Her temperature is 37.8°C (100.04°F), pulse is 111/min, respirations are 18/min, blood pressure is 130/60 mmHg. She is heparinized to treat the suspected pulmonary embolism and started on a long-term prophylactic agent. Shortly after, the patient's clinical condition deteriorates (see image below). 




Which of the following abnormalities is the most likely cause of these findings?

External References