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Bacterial structure and functions
Bacillus anthracis (Anthrax)
Bacillus cereus (Food poisoning)
Corynebacterium diphtheriae (Diphtheria)
Clostridium botulinum (Botulism)
Clostridium difficile (Pseudomembranous colitis)
Clostridium tetani (Tetanus)
Streptococcus agalactiae (Group B Strep)
Streptococcus pyogenes (Group A Strep)
Bartonella henselae (Cat-scratch disease and Bacillary angiomatosis)
Legionella pneumophila (Legionnaires disease and Pontiac fever)
Salmonella typhi (typhoid fever)
Yersinia pestis (Plague)
Vibrio cholerae (Cholera)
Bordetella pertussis (Whooping cough)
Francisella tularensis (Tularemia)
Haemophilus ducreyi (Chancroid)
Mycobacterium tuberculosis (Tuberculosis)
Mycobacterium avium complex (NORD)
Gardnerella vaginalis (Bacterial vaginosis)
Coxiella burnetii (Q fever)
Ehrlichia and Anaplasma
Rickettsia rickettsii (Rocky Mountain spotted fever) and other Rickettsia species
Borrelia burgdorferi (Lyme disease)
Borrelia species (Relapsing fever)
Treponema pallidum (Syphilis)
0 / 37 complete
0 / 7 complete
Pseudomonas Aeruginosa Characteristics
Pseudomonas Aeruginosa Disease
Pseudomonas aeruginosa p. , 141, 731
Pseudomonas aeruginosa p. , 141
Pseudomonas aeruginosa p. , 130
aerobic organism p. 124
biofilm production p. 127
encapsulated p. 125
exotoxin production p. 130
immunodeficient patients p. 116
multidrug-resistant p. 194
nosocomial infection p. 182
pigment production p. 127
pyocyanin of p. 107
splenic dysfunction and p. 96
UTIs p. 179
Pseudomonas aeruginosa, or P. aeruginosa, is a gram-negative bacterium that is abundant in the environment.
It tends to opportunistically infect high-risk individuals, and is well known for its multi-drug resistance, making it hard to treat.
P. aeruginosa is an encapsulated, gram-negative, rod bacterium, that’s an obligate aerobe, so it uses oxygen for metabolism through cellular respiration.
It does not ferment lactose and does not make spores; but it’s catalase, citrate, and oxidase positive.
It has a flagellum, kind of like a tail, at one end for motility; and has multiple hair-like appendages, called pili, all over that help with adhesion to other cells.
It also has a number of multidrug efflux pumps that efficiently pump medications out of the bacteria making it resistant to a variety of antibiotics.
In addition it’s able to make beta-lactamases that degrade beta-lactam antibiotics as well as aminoglycoside-modifying enzymes that alter aminoglycoside antibiotics - rendering them ineffective. In short, it’s defenses are strong.
P. aeruginosa is everywhere in the environment - in soil; in the home, and in hospitals - where it’s found on improperly cleaned medical equipment and devices, various surfaces, and on the hands of health care workers.
It can survive for months on dry surfaces and inanimate objects – but particularly loves humid or wet conditions; like hot tubs, contact lens cases, catheters, and medical ventilators.
Transmission can occur when broken skin or mucous membranes come in contact with contaminated surfaces; or when aerosols containing P. aeruginosa are inhaled after an infected person coughs or sneezes.
Now, a P. aeruginosa infection is actually not too common in the general population.
It’s an opportunistic bacterium, meaning that it frequently causes infections in high-risk individuals like those with cystic fibrosis, chronic granulomatous disease, and type 2 diabetes mellitus.
It’s also common among individuals with an immunodeficiency; IV drug abusers, or those with severe burns or deep wounds.
Pseudomonas aeruginosa is an aerobic, gram-negative, rod-shaped bacterium commonly found in the environment, such as in soil, in the home, and in hospitals. It is known to opportunistically infect immunocompromised people, and for its multi-drug resistance that is hard to treat.
It is also known to form biofilms that provide it with extra protection against antibiotics on top of its preexisting multi-drug resistance. P. aeruginosa can cause a variety of infections, including urinary tract infections, wound infections, sepsis, and lung infections in people with cystic fibrosis. Treatment for P. aeruginosa infections is with antibiotics, such as aminoglycosides, carbapenems, and cephalosporins.
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