Pulmonary hypertension is an increase of blood pressure in the pulmonary artery, pulmonary vein, or pulmonary capillaries, together known as the lung vasculature, leading to shortness of breath, dizziness, fainting, leg swelling and other symptoms. It is defined as pulmonary hypertension at or greater than 25 mm Hg at rest. Pulmonary hypertension can be a severe disease with a markedly decreased exercise tolerance. Long term disease can result in arteriosclerosis, medial hypertrophy, and intimal fibrosis of pulmonary arteries. It can further result in right heart failure, and death from decompensated cor pulmonale.
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