AssessmentsPyruvate kinase deficiency
Pyruvate kinase deficiency
USMLE® Step 1 style questions USMLE
A 45-year-old man comes to the primary care office because of a three-month history of progressive fatigue, abdominal pain, and darker-than-normal urine, especially in the morning. Temperature is 37°C (98.6°F), pulse is 80/min, respirations are 12/min, and blood pressure is 128/82 mmHg. Physical examination is within normal limits. Laboratory tests are obtained, and the results are shown below.
Sucrose hemolysis test is positive. The patient's condition is most likely attributed to which of the following?