Renal agenesis is a medical condition in which fetal kidneys fail to develop, it may be either unilateral or bilateral. This results in the absence of one or both kidneys, which can lead to several complications. Bilateral renal agenesis is incompatible with life because prolonged absence of amniotic fluid results in pulmonary hypoplasia leading to severe respiratory insufficiency at birth.
People with unilateral renal agenesis may have no symptoms, while others may experience symptoms such as high blood pressure, swelling, and difficulty urinating. Diagnosis of renal agenesis can be done through imaging tests such as ultrasound, CT scan, or MRI. Treatment typically involves managing symptoms and complications, such as high blood pressure and kidney failure. In cases of bilateral renal agenesis, dialysis or a kidney transplant may be necessary.
- "Robbins Basic Pathology" Elsevier (2017)
- "Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2)" McGraw-Hill Education / Medical (2018)
- "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
- "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
- "Control of Murine Kidney Development by Sonic Hedgehog and its GLI Effectors" Cell Cycle (2006)
- "A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans" Genetics (2017)
- "Special Imaging Casebook" Journal of Perinatology (2000)