Renal papillary necrosis
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Summary of Renal papillary necrosis
Renal papillary necrosis is a nephropathy resulting from impaired blood supply leading to diffuse necrosis of the renal papilla. Lesions that characterize renal papillary necrosis come from an impairment of the blood supply and from subsequent ischemic necrosis that is diffuse. The pathophysiology of this condition can be due to analgesic nephropathy, which in turn is a result of long-term use of aspirin.
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Pathology
Renal system
Renal and ureteral disorders
Renal agenesis
Horseshoe kidney
Potter sequence
Hyperphosphatemia
Hypophosphatemia
Hypernatremia
Hyponatremia
Hypermagnesemia
Hypomagnesemia
Hyperkalemia
Hypokalemia
Hypercalcemia
Hypocalcemia
Renal tubular acidosis
Minimal change disease
Diabetic nephropathy
Focal segmental glomeruloscerosis (NORD)
Amyloidosis
Membranous nephropathy
Lupus nephritis
Membranoproliferative glomerulonephritis
Poststreptococcal glomerulonephritis
Rapidly progressive glomerulonephritis
IgA nephropathy (NORD)
Lupus nephritis
Alport syndrome
Kidney stones
Hydronephrosis
Acute pyelonephritis
Chronic pyelonephritis
Prerenal azotemia
Renal azotemia
Acute tubular necrosis
Postrenal azotemia
Renal papillary necrosis
Renal cortical necrosis
Chronic kidney disease
Polycystic kidney disease
Multicystic dysplastic kidney
Medullary cystic kidney disease
Medullary sponge kidney
Renal artery stenosis
Renal cell carcinoma
Angiomyolipoma
Nephroblastoma (Wilms tumor)
WAGR syndrome
Beckwith-Wiedemann syndrome
Bladder and urethral disorders
Renal system pathology review
Congenital renal disorders: Pathology review
Renal tubular defects: Pathology review
Renal tubular acidosis: Pathology review
Acid-base disturbances: Pathology review
Electrolyte disturbances: Pathology review
Renal failure: Pathology review
Nephrotic syndromes: Pathology review
Nephritic syndromes: Pathology review
Urinary incontinence: Pathology review
Urinary tract infections: Pathology review
Kidney stones: Pathology review
Renal and urinary tract masses: Pathology review
AssessmentsRenal papillary necrosis
Renal papillary necrosis
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Renal papillary necrosis
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A 56-year-old woman comes to the office because of a 1-week history of left flank pain. Her medical history is relevant for fibromyalgia and osteoarthritis. She currently takes low-dose aspirin, acetaminophen, and ibuprofen. Upon further interrogation, the patient claims no relief of her symptoms despite taking more pain medication than usual. She also noticed an increased urinary frequency and "cloudy and pink" urine. Physical exam shows dry skin and conjunctivae. Her temperature is 36.5°C (97.7°F), pulse is 91/min, respirations are 16/min, blood pressure is 140/90 mmHg. An abdominal CT scan reveals an atrophic and small left kidney with papillary calcifications. This patient most likely has which of the following conditions?
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