Rotor syndrome
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Rotor syndrome
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Rotor syndrome
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Rotor syndrome
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USMLE® Step 1 style questions USMLE
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Reproduced from: Wikimedia Commons
Cardiac and pulmonary exams are noncontributory. Serum carbohydrate antigen 19-9 levels are elevated. Which of the following laboratory findings would most likely be present in this patient?
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Rotor syndrome p. 402, 402
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Summary
Rotor syndrome is a rare, relatively benign autosomal recessive bilirubin disorder. It is caused by mutations in SLCO1B1 and SLCO1B3 genes, which leads to conjugated and unconjugated hyperbilirubinemia, with no hemolysis. Signs and symptoms of Rotor syndrome include recurrent jaundice, which initially presents soon after birth or during childhood. Typically, there is no treatment required.
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