Ruptured spleen

A splenic injury, which includes a ruptured spleen, can be caused by trauma. In minor injuries with little bleeding, there may be abdominal pain, tenderness in the epigastrium and pain in the left flank. Often there is a sharp pain in the left shoulder, known as Kehr's sign. Non-traumatic causes are less common and include infectious diseases, medical procedures such as colonoscopy, hematological diseases, medications, and pregnancy. In less than one percent of cases of infectious mononucleosis splenic rupture may occur.