Ruptured spleen

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Ruptured spleen

Pathology

General infections

Sepsis

Neonatal sepsis

Abscesses

Hypersensitivity reactions

Type I hypersensitivity

Food allergy

Anaphylaxis

Asthma

Type II hypersensitivity

Immune thrombocytopenic purpura

Autoimmune hemolytic anemia

Hemolytic disease of the newborn

Goodpasture syndrome

Rheumatic heart disease

Myasthenia gravis

Graves disease

Pemphigus vulgaris

Type III hypersensitivity

Serum sickness

Systemic lupus erythematosus

Poststreptococcal glomerulonephritis

Type IV hypersensitivity

Graft-versus-host disease

Contact dermatitis

Transplants

Transplant rejection

Graft-versus-host disease

Cytomegalovirus infection after transplant (NORD)

Post-transplant lymphoproliferative disorders (NORD)

Immunodeficiences

X-linked agammaglobulinemia

Selective immunoglobulin A deficiency

Common variable immunodeficiency

IgG subclass deficiency

Hyperimmunoglobulin E syndrome

Isolated primary immunoglobulin M deficiency

Thymic aplasia

DiGeorge syndrome

Severe combined immunodeficiency

Adenosine deaminase deficiency

Ataxia-telangiectasia

Hyper IgM syndrome

Wiskott-Aldrich syndrome

Leukocyte adhesion deficiency

Chediak-Higashi syndrome

Chronic granulomatous disease

Complement deficiency

Hereditary angioedema

Asplenia

Immune system organ disorders

Thymoma

Ruptured spleen

Immune system pathology review

Blood transfusion reactions and transplant rejection: Pathology review

Immunodeficiencies: T-cell and B-cell disorders: Pathology review

Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review

Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review

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Ruptured spleen

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Summary

A ruptured spleen is a medical emergency that occurs when the spleen, an organ located in the upper left side of the abdomen, tears open. This can result in intra abdominal bleeding, abdominal pain, dizziness, shortness of breath, and feeling faint.

Causes of spleen rupture may be traumatic., or nontraumatic. Among traumatic causes include blunt and penetrating abdominal injuries. Non-traumatic causes are less common and include infectious diseases, medical procedures such as colonoscopies, hematological diseases, medications, and pregnancy. Treatment typically involves surgery to repair or remove the spleen, followed by antibiotics to reduce the risk of infection.

Elsevier

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