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Acoustic neuroma (schwannoma)
Adult brain tumors
Pediatric brain tumors
Transient ischemic attack
Cavernous sinus thrombosis
Spinocerebellar ataxia (NORD)
Tethered spinal cord syndrome
Lewy body dementia
Normal pressure hydrocephalus
Acute disseminated encephalomyelitis
Central pontine myelinolysis
JC virus (Progressive multifocal leukoencephalopathy)
Cavernous sinus thrombosis
Idiopathic intracranial hypertension
Opsoclonus myoclonus syndrome (NORD)
Restless legs syndrome
Early infantile epileptic encephalopathy (NORD)
Cauda equina syndrome
Treponema pallidum (Syphilis)
Vitamin B12 deficiency
Concussion and traumatic brain injury
Spinal muscular atrophy
Carpal tunnel syndrome
Thoracic outlet syndrome
Lambert-Eaton myasthenic syndrome
Adult brain tumors: Pathology review
Central nervous system infections: Pathology review
Cerebral vascular disease: Pathology review
Congenital neurological disorders: Pathology review
Dementia: Pathology review
Demyelinating disorders: Pathology review
Headaches: Pathology review
Movement disorders: Pathology review
Neurocutaneous disorders: Pathology review
Neuromuscular junction disorders: Pathology review
Pediatric brain tumors: Pathology review
Seizures: Pathology review
Spinal cord disorders: Pathology review
Traumatic brain injury: Pathology review
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Sciatica is a condition where there’s pain that starts in the lower back which then travels down the leg. Since the pain is associated with injury or compression of the sciatic nerve and follows the path of the sciatic nerve, it makes sense to name it sciatica.
The sciatic nerve is the longest and widest nerve in the body. It’s formed by the spinal nerves L4, L5, and S1-3, which leave the spinal canal through intervertebral foramen, an opening located between the vertebrae and behind the intervertebral discs. These nerves travel to the area in front of the sacrum, and join to make the sacral plexus.
All the nerves in the plexus, except S3 are split into two divisions: anterior and posterior. Anterior divisions of the L4, L5, S1, S2 and the entire S3 nerve create the tibial nerve, while posterior divisions of the L4, L5, S1 and S2 form the common fibular nerve. These two nerves are bound together by connective tissue and make up the sciatic nerve.
It then travels down the back of the thigh to the back of the knee where it splits into the tibial and common fibular nerves. The sciatic nerve innervates the muscles in the back of the thigh. The Tibial nerve innervates the muscles of the posterior compartment of the leg and intrinsic flexors of the foot.
The Common fibular nerve is in charge of the muscles in the anterior and lateral compartments of the leg and intrinsic extensors of the foot. Now, each spinal nerve is in charge of the sensation of a specific area of the skin, called a dermatome.
Sciatica is a term used to describe symptoms of lower back pain, numbness, or tingling that originate in the lower back and travel down the sciatic nerve. It is often due to a spinal disc herniation pressing on one of the lumbar or sacral nerve roots. Other common causes are spinal stenosis, degenerative disc diseases. Treatment options include physical therapy, pain medication, exercise, and in some cases, surgery.
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