Scleroderma
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High Yield Notes
13 pages
Flashcards
Scleroderma
of complete
Questions
USMLE® Step 1 style questions USMLE
of complete
Image reproduced from Radiopedia
Which of the following findings is most likely to be seen in this patient?
Memory Anchors and Partner Content
External References
First Aid
2024
2023
2022
2021
Anti-centromere antibodies p. 724
scleroderma p. 481
CREST syndrome (limited scleroderma)
Diffuse scleroderma p. 481
Limited scleroderma p. 481
Limited scleroderma (CREST syndrome)
Scleroderma p. 481
labs/findings p. 724, 728
Scleroderma (diffuse)
autoantibody p. 113
Summary
Scleroderma, also known as systemic sclerosis, is a chronic systemic autoimmune disease characterized by progressive fibrosis of skin and internal organs such as the gastrointestinal tract, lungs, heart, and kidneys. The exact cause is unknown but is associated with autoimmune processes that lead to excessive collagen production in individuals with a genetic predisposition. Scleroderma can be either limited or diffuse, with symptoms varying according to the organs involved. Treatment options involve immunosuppressants and medications to relieve symptoms and slow the progression of the disease.
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