Type I hypersensitivity
Autoimmune hemolytic anemia
Hemolytic disease of the newborn
Rheumatic heart disease
Type II hypersensitivity
Systemic lupus erythematosus
Type III hypersensitivity
Type IV hypersensitivity
Common variable immunodeficiency
Hyperimmunoglobulin E syndrome
IgG subclass deficiency
Isolated primary immunoglobulin M deficiency
Selective immunoglobulin A deficiency
Adenosine deaminase deficiency
Hyper IgM syndrome
Severe combined immunodeficiency
Cytomegalovirus infection after transplant (NORD)
Post-transplant lymphoproliferative disorders (NORD)
Chronic granulomatous disease
Leukocyte adhesion deficiency
Blood transfusion reactions and transplant rejection: Pathology review
Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review
Immunodeficiencies: T-cell and B-cell disorders: Pathology review
0 / 1 complete
septic p. 478
acute tubular necrosis p. 627
ARDS p. NaN
immunodeficient patients p. 116
lymphopenia with p. 431
neutropenia with p. 431
shock with p. 321
Streptococcus agalactiae as cause p. 135
Listeria monocytogenes p. , 137
readmissions with p. 277
Waterhouse-Friderichsen syndrome p. 355
Sepsis is a potentially life-threatening condition that occurs when an infection spreads through the bloodstream and triggers a widespread immune response. The body's normal immune response to infection can sometimes become overactive, leading to widespread inflammation, which can cause tissue damage and affect organ function.
Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. There may also be symptoms related to a specific infection, such as a cough with pneumonia, or painful urination with a kidney infection. In the very young, old, and people with a weakened immune system, there may be no symptoms of a specific infection and the body temperature may be low or normal rather than high.
Insufficient blood flow may be evident by low blood pressure, high blood lactate, or low urine output. Septic shock is low blood pressure due to sepsis that does not improve after reasonable amounts of intravenous fluids are given. Treatment for sepsis typically involves antibiotics to treat the underlying infection, as well as supportive care to address the symptoms and prevent complications.
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