Serotonin syndrome
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Serotonin syndrome
Psychological disorders
Bipolar and related disorders
Bipolar disorder
Medication-induced movement disorders and other adverse effects of medication
Neuroleptic malignant syndrome
Serotonin syndrome
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Serotonin syndrome
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Serotonin syndrome
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External References
First Aid
2022
2021
2020
2019
2018
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2016
Autonomic nervous system
in serotonin syndrome p. 592
Serotonin syndrome p. 409, 567, 573, 593
dextromethorphan p. 711
MAO inhibitors p. 599
MDMA p. 595
oxazolidinones p. 190
Summary
Serotonin syndrome is a potentially life-threatening condition that occurs when there is an excess of serotonin, a neurotransmitter in the brain, leading to a dangerous increase in nerve cell activity. Serotonin syndrome can occur as a result of taking certain medications, including selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) or taking a combination of medications that increase serotonin levels. Symptoms include agitation, confusion, muscle rigidity and hyperreflexia, hypertension, dysrhythmias, diaphoresis, and tachypnea. Treatment may include discontinuing the culprit drug, supportive management, and providing cyproheptadine.
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