Sickle cell disease (NORD)
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Pathology
Hematological system
Anemias
Iron deficiency anemia
Alpha-thalassemia
Sideroblastic anemia
Anemia of chronic disease
Lead poisoning
Hemolytic disease of the newborn
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
Autoimmune hemolytic anemia
Pyruvate kinase deficiency
Paroxysmal nocturnal hemoglobinuria
Sickle cell disease (NORD)
Hereditary spherocytosis
Anemia of chronic disease
Aplastic anemia
Fanconi anemia
Megaloblastic anemia
Folate (Vitamin B9) deficiency
Vitamin B12 deficiency
Fanconi anemia
Diamond-Blackfan anemia
Heme synthesis disorders
Coagulation disorders
Platelet disorders
Mixed platelet and coagulation disorders
Thrombosis syndromes (hypercoagulability)
Lymphomas
Leukemias
Leukemoid reaction
Dysplastic and proliferative disorders
Plasma cell dyscrasias
Hematological system pathology review
Microcytic anemia: Pathology review
Non-hemolytic normocytic anemia: Pathology review
Intrinsic hemolytic normocytic anemia: Pathology review
Extrinsic hemolytic normocytic anemia: Pathology review
Macrocytic anemia: Pathology review
Heme synthesis disorders: Pathology review
Coagulation disorders: Pathology review
Platelet disorders: Pathology review
Mixed platelet and coagulation disorders: Pathology review
Thrombosis syndromes (hypercoagulability): Pathology review
Lymphomas: Pathology review
Leukemias: Pathology review
Plasma cell disorders: Pathology review
Myeloproliferative disorders: Pathology review
AssessmentsSickle cell disease (NORD)
Sickle cell disease (NORD)
Flashcards
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Questions
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Flashcards
Sickle cell disease (NORD)
17 flashcards
Questions
USMLE® Step 1 style questions USMLE
12 questions
USMLE® Step 2 style questions USMLE
5 questions
Preview
A 3-year-old boy is brought to the clinic by his mother for a check-up. Recent laboratory data has demonstrated a persistent normocytic anemia, with the most recent hematocrit is 32.1%. A peripheral blood smear is suggestive of a hemolytic anemia. His mother reports occasional difficulty with breathing, intermittent chest pain, and occasional pain in his fingers. The patient’s mother is concerned about these intermittent episodes and asks about the possibility of an underlying disease. Evaluation of the patient’s peripheral blood under high-powered microscopy is demonstrated distortions of the red blood cell architecture. Which of the following pathophysiologic mechanisms best describes the underlying disease?
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