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Pathology
Choanal atresia
Laryngomalacia
Allergic rhinitis
Nasal polyps
Upper respiratory tract infection
Sinusitis
Laryngitis
Retropharyngeal and peritonsillar abscesses
Bacterial epiglottitis
Nasopharyngeal carcinoma
Tracheoesophageal fistula
Congenital pulmonary airway malformation
Pulmonary hypoplasia
Neonatal respiratory distress syndrome
Transient tachypnea of the newborn
Meconium aspiration syndrome
Apnea of prematurity
Sudden infant death syndrome
Acute respiratory distress syndrome
Pulmonary changes at high altitude and altitude sickness
Decompression sickness
Cyanide poisoning
Methemoglobinemia
Emphysema
Chronic bronchitis
Asthma
Cystic fibrosis
Bronchiectasis
Alpha 1-antitrypsin deficiency
Restrictive lung diseases
Sarcoidosis
Idiopathic pulmonary fibrosis
Hypersensitivity pneumonitis
Pneumonia
Croup
Bacterial tracheitis
Lung cancer
Pancoast tumor
Superior vena cava syndrome
Pneumothorax
Pleural effusion
Mesothelioma
Pulmonary embolism
Pulmonary edema
Pulmonary hypertension
Sleep apnea
Apnea of prematurity
Respiratory distress syndrome: Pathology review
Cystic fibrosis: Pathology review
Pneumonia: Pathology review
Tuberculosis: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Obstructive lung diseases: Pathology review
Restrictive lung diseases: Pathology review
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Lung cancer and mesothelioma: Pathology review
Sinusitis
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rhinosinusitis p. 697
rhinosinusitis p. 697
brain abscesses p. 177
C3 deficiency and p. 105
Kartagener syndrome p. 47, 714
Wegener granulomatosis p. 322
rhinosinusitis p. 697
Sinusitis is inflammation of the paranasal sinuses - which are pairs of air spaces that surround the nose in the front of the face.
Usually, acute sinusitis can last up to four weeks, subacute sinusitis lasts between 1 to 3 months, and chronic sinusitis lasts more than 3 months.
When you breathe in, air flows through the nostrils and enters the nasal cavity, which is lined by goblet cells that release mucus.
That mucus is salty, sticky, and contains lysozymes, which are enzymes that help kill bacteria.
Nose hairs at the entrance of the nasal cavity get coated with that mucus and are able to trap large particles of dust and pollen as well as bacteria, forming tiny clumps of boogers.
The nasal cavity is connected to four paired paranasal sinuses, named according to the bones in which they lie.
The largest are the maxillary sinuses, found right below the eyes.
Then we have the ethmoidal and sphenoidal sinuses behind the eyes.
Finally, the frontal sinuses are in the forehead, right above the eyes.
The paranasal sinuses act like tiny echo-chambers that help amplify the sound of your voice, which is why you sound so different when they’re clogged with mucus during a cold!
They also allow the inspired air to circulate for a bit so it has time to get warm and moist.
Like the rest of the respiratory tract, the walls of the paranasal sinuses are made up of a mucosal epithelium.
The mucosal epithelium contains goblet cells, which produce mucus to trap small foreign particles, as well as columnar cells, which have cilia, which are tiny little hair like projections that move mucus, draining into the nasal passages.
One of these passages is also called a nasal meatus, and there are three; the superior, middle, and inferior meatus which help drain mucus.
Sinusitis is a common condition in which the paranasal sinuses become inflamed, which makes it more difficult for them to drain. The condition can be caused by a viral, bacterial, or fungal infection, or by other factors such as allergies. Symptoms of sinusitis include facial pain, headaches, fevers, congestion, nasal discharge, and a cough that's typically worse at night. Treatment may include antibiotics, decongestants, and pain relievers. In some cases, sinus surgery may be necessary to open up the wall of the infected sinus to allow it to drain more easily into the nasal cavity.
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