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Apnea of prematurity
Acute respiratory distress syndrome
Pulmonary changes at high altitude and altitude sickness
Congenital pulmonary airway malformation
Superior vena cava syndrome
Meconium aspiration syndrome
Neonatal respiratory distress syndrome
Sudden infant death syndrome
Transient tachypnea of the newborn
Alpha 1-antitrypsin deficiency
Idiopathic pulmonary fibrosis
Restrictive lung diseases
Retropharyngeal and peritonsillar abscesses
Upper respiratory tract infection
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Cystic fibrosis: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Lung cancer and mesothelioma: Pathology review
Obstructive lung diseases: Pathology review
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Pneumonia: Pathology review
Respiratory distress syndrome: Pathology review
Restrictive lung diseases: Pathology review
Tuberculosis: Pathology review
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rhinosinusitis p. 693
brain abscesses p. 177
C3 deficiency and p. 105
Kartagener syndrome p. 47, 722
Wegener granulomatosis p. 322
Sinusitis is inflammation of the paranasal sinuses - which are pairs of air spaces that surround the nose in the front of the face.
Usually, acute sinusitis can last up to four weeks, subacute sinusitis lasts between 1 to 3 months, and chronic sinusitis lasts more than 3 months.
When you breathe in, air flows through the nostrils and enters the nasal cavity, which is lined by goblet cells that release mucus.
That mucus is salty, sticky, and contains lysozymes, which are enzymes that help kill bacteria.
Nose hairs at the entrance of the nasal cavity get coated with that mucus and are able to trap large particles of dust and pollen as well as bacteria, forming tiny clumps of boogers.
The nasal cavity is connected to four paired paranasal sinuses, named according to the bones in which they lie.
The largest are the maxillary sinuses, found right below the eyes.
Then we have the ethmoidal and sphenoidal sinuses behind the eyes.
Finally, the frontal sinuses are in the forehead, right above the eyes.
The paranasal sinuses act like tiny echo-chambers that help amplify the sound of your voice, which is why you sound so different when they’re clogged with mucus during a cold!
They also allow the inspired air to circulate for a bit so it has time to get warm and moist.
Like the rest of the respiratory tract, the walls of the paranasal sinuses are made up of a mucosal epithelium.
The mucosal epithelium contains goblet cells, which produce mucus to trap small foreign particles, as well as columnar cells, which have cilia, which are tiny little hair like projections that move mucus, draining into the nasal passages.
One of these passages is also called a nasal meatus, and there are three; the superior, middle, and inferior meatus which help drain mucus.
Sinusitis is a common condition in which the paranasal sinuses become inflamed, which makes it more difficult for them to drain. The condition can be caused by a viral, bacterial, or fungal infection, or by other factors such as allergies. Symptoms of sinusitis include facial pain, headaches, fevers, congestion, nasal discharge, and a cough that's typically worse at night. Treatment may include antibiotics, decongestants, and pain relievers. In some cases, sinus surgery may be necessary to open up the wall of the infected sinus to allow it to drain more easily into the nasal cavity.
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