Somatostatin

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Somatostatin

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Acromegaly p. 343

somatostatin analogs for p. 333

somatostatin for p. 360

Carcinoid syndrome p. 354, 586

somatostatin for p. 360

Δ cells

somatostatinomas of p. 355

somatostatin production p. 378

Glucagon p. 333

somatostatin and p. 378

somatostatinomas and p. 355

Glucagonomas p. 356

somatostatin for p. 362

Growth hormone (GH) p. 338, 362

somatostatin p. 341

Insulin p. 333

somatostatin and p. 378

somatostatinomas and p. 355

Pepsinogen

somatostatin and p. 378

Somatostatin

glucagon and p. 333

hypothalamic/pituitary drugs p. 362

hypothalamic-pituitary hormones p. 332

production of p. 335

regulatory substances p. 378

secretory cell locations p. 380

Summary

Somatostatin is a peptide hormone that is produced and secreted by several different cells in the body, such as in the pancreas, the gastrointestinal tract, the hypothalamus, and the central nervous system.

Somatostatin acts as an inhibitory hormone, meaning that it reduces the activity of other hormones such as the growth hormone and insulin. It is also involved in slowing down the activity of the digestive system, by inhibiting the secretion of gastric hormones (e.g. gastrin and cholecystokinin) and decreasing gastrointestinal motility.