Somatostatin
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Somatostatin
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Acromegaly p. 343
somatostatin analogs for p. 333
somatostatin for p. 360
Carcinoid syndrome p. 354, 586
somatostatin for p. 360
Δ cells
somatostatinomas of p. 355
somatostatin production p. 378
Glucagon p. 333
somatostatin and p. 378
somatostatinomas and p. 355
Glucagonomas p. 356
somatostatin for p. 362
Growth hormone (GH) p. 338, 362
somatostatin p. 341
Insulin p. 333
somatostatin and p. 378
somatostatinomas and p. 355
Pepsinogen
somatostatin and p. 378
Somatostatin
glucagon and p. 333
hypothalamic/pituitary drugs p. 362
hypothalamic-pituitary hormones p. 332
production of p. 335
regulatory substances p. 378
secretory cell locations p. 380
Summary
Somatostatin is a peptide hormone that is produced and secreted by several different cells in the body, such as in the pancreas, the gastrointestinal tract, the hypothalamus, and the central nervous system.
Somatostatin acts as an inhibitory hormone, meaning that it reduces the activity of other hormones such as the growth hormone and insulin. It is also involved in slowing down the activity of the digestive system, by inhibiting the secretion of gastric hormones (e.g. gastrin and cholecystokinin) and decreasing gastrointestinal motility.